Chondroitin sulfate proteoglycan serglycin influences protein cargo loading and functions of tumor-derived exosomes

Tumor cells produce and utilize exosomes to promote tumor growth and metastasis. Tumor-cell-derived exosomes deliver cargos that partially mimic the contents of the parent cell to nearby or distant normal or abnormal cells, thereby reprogramming the recipient cells to support tumor progression. Mech...

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Veröffentlicht in:	Oncotarget 2017-09, Vol.8 (43), p.73723-73732
Hauptverfasser:	Purushothaman, Anurag, Bandari, Shyam K, Chandrashekar, Darshan S, Jones, Richard J, Lee, Hans C, Weber, Donna M, Orlowski, Robert Z
Format:	Artikel
Sprache:	eng
Schlagworte:	Research Paper
Online-Zugang:	Volltext
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