Comparative Evaluation of Subtyping Tools for Surveillance of Newly Emerging HIV-1 Strains

HIV-1 non-B subtypes/circulating recombinant forms (CRFs) are increasing worldwide. Since subtype identification can be clinically relevant, we assessed the added value in HIV-1 subtyping using updated molecular phylogeny (Mphy) and the performance of routinely used automated tools. Updated Mphy (20...

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Veröffentlicht in:	Journal of clinical microbiology 2017-09, Vol.55 (9), p.2827-2837
Hauptverfasser:	Fabeni, Lavinia, Berno, Giulia, Fokam, Joseph, Bertoli, Ada, Alteri, Claudia, Gori, Caterina, Forbici, Federica, Takou, Desiré, Vergori, Alessandra, Zaccarelli, Mauro, Maffongelli, Gaetano, Borghi, Vanni, Latini, Alessandra, Pennica, Alfredo, Mastroianni, Claudio Maria, Montella, Francesco, Mussini, Cristina, Andreoni, Massimo, Antinori, Andrea, Perno, Carlo Federico, Santoro, Maria Mercedes
Format:	Artikel
Sprache:	eng
Schlagworte:	Automation, Laboratory Base Sequence Databases, Genetic HIV Infections - diagnosis HIV Infections - virology HIV Protease - genetics HIV Reverse Transcriptase - genetics HIV-1 - classification HIV-1 - genetics Humans Molecular Typing - methods Phylogeny Sensitivity and Specificity Sequence Analysis, RNA Virology
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