Metabolic Instruction of Immunity

Choices have consequences. Immune cells survey and migrate throughout the body and sometimes take residence in niche environments with distinct communities of cells, extracellular matrix, and nutrients that may differ from those in which they matured. Imbedded in immune cell physiology are metabolic...

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Veröffentlicht in:	Cell 2017-05, Vol.169 (4), p.570-586
Hauptverfasser:	Buck, Michael D., Sowell, Ryan T., Kaech, Susan M., Pearce, Erika L.
Format:	Artikel
Sprache:	eng
Schlagworte:	aerobic glycolysis Animals barrier immunity checkpoint blockade Gastrointestinal Tract - cytology Gastrointestinal Tract - immunology Humans immunometabolism immunotherapy Leukocytes - cytology Leukocytes - immunology Leukocytes - metabolism metabolism mitochondria mitochondrial dynamics mucosa T-Lymphocytes - immunology Tumor Microenvironment
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