Sorafenib in Japanese Patients with Locally Advanced or Metastatic Medullary Thyroid Carcinoma and Anaplastic Thyroid Carcinoma

Background: Therapeutic options for treating advanced or metastatic medullary thyroid carcinoma (MTC) and anaplastic thyroid carcinoma (ATC) are still limited in Japan, even though vandetanib for MTC and lenvatinib for MTC and ATC have been approved. Sorafenib is an oral multikinase inhibitor approv...

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Veröffentlicht in:	Thyroid (New York, N.Y.) N.Y.), 2017-09, Vol.27 (9), p.1142-1148
Hauptverfasser:	Ito, Yasuhiro, Onoda, Naoyoshi, Ito, Ken-ichi, Sugitani, Iwao, Takahashi, Shunji, Yamaguchi, Iku, Kabu, Koki, Tsukada, Katsuya
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alopecia - chemically induced Alopecia - ethnology Antineoplastic Agents - adverse effects Antineoplastic Agents - therapeutic use Carcinoma, Neuroendocrine - drug therapy Carcinoma, Neuroendocrine - ethnology Carcinoma, Neuroendocrine - pathology Carcinoma, Neuroendocrine - secondary Diarrhea - chemically induced Diarrhea - ethnology Drug Resistance, Neoplasm Female Hand-Foot Syndrome - ethnology Hand-Foot Syndrome - etiology Humans Hypertension - chemically induced Hypertension - ethnology Japan Male Neoplasm Grading Niacinamide - adverse effects Niacinamide - analogs & derivatives Niacinamide - therapeutic use Patient Dropouts - ethnology Phenylurea Compounds - adverse effects Phenylurea Compounds - therapeutic use Protein Kinase Inhibitors - adverse effects Protein Kinase Inhibitors - therapeutic use Survival Analysis Thyroid Cancer and Nodules Thyroid Carcinoma, Anaplastic - drug therapy Thyroid Carcinoma, Anaplastic - ethnology Thyroid Carcinoma, Anaplastic - pathology Thyroid Gland - drug effects Thyroid Gland - pathology Thyroid Neoplasms - drug therapy Thyroid Neoplasms - ethnology Thyroid Neoplasms - pathology Thyroid Neoplasms - secondary Tumor Burden - drug effects
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