Genomics alterations of metastatic and primary tissues across 15 cancer types

Metastasis is an important event for cancer evolution and prognosis. In this article, we analyzed the differences in genomic alterations between primary and metastatic tissues at hotspot regions in 15 cancer types and 10,456 samples. Differential somatic mutations at the amino acid, protein domain a...

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Veröffentlicht in:	Scientific reports 2017-10, Vol.7 (1), p.13262-9, Article 13262
Hauptverfasser:	Liu, Gang, Zhan, Xiaohui, Dong, Chuanpeng, Liu, Lei
Format:	Artikel
Sprache:	eng
Schlagworte:	45/23 631/67/68 631/67/69 Amino acids Cancer Cell migration Copy number Gene fusion Genomics Heterogeneity Humanities and Social Sciences Metastases Metastasis multidisciplinary Science Science (multidisciplinary)
Online-Zugang:	Volltext
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