Utility of CT oral contrast administration in the emergency department of a quaternary oncology hospital: diagnostic implications, turnaround times, and assessment of ED physician ordering

Purpose To compare studies with and without oral contrast on performance of multidetector computed tomography (CT) and the order to CT examination turnaround time in cancer patients presenting to the emergency department (ED). To the best of our knowledge, oral contrast utility has not previously be...

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Veröffentlicht in:Abdominal imaging 2017-11, Vol.42 (11), p.2760-2768
Hauptverfasser: Jensen, Corey T., Blair, Katherine J., Le, Ott, Sun, Jia, Wei, Wei, Korivi, Brinda Rao, Morani, Ajaykumar C., Wagner-Bartak, Nicolaus A.
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container_end_page 2768
container_issue 11
container_start_page 2760
container_title Abdominal imaging
container_volume 42
creator Jensen, Corey T.
Blair, Katherine J.
Le, Ott
Sun, Jia
Wei, Wei
Korivi, Brinda Rao
Morani, Ajaykumar C.
Wagner-Bartak, Nicolaus A.
description Purpose To compare studies with and without oral contrast on performance of multidetector computed tomography (CT) and the order to CT examination turnaround time in cancer patients presenting to the emergency department (ED). To the best of our knowledge, oral contrast utility has not previously been specifically assessed in cancer patients presenting to the emergency department. Materials & methods Retrospective review of CT abdomen examinations performed in oncology patients presenting to the emergency department during one month. CT examinations performed with and without oral contrast were rated by two consensus readers for degree of confidence and diagnostic ability. Correlations were assessed for primary cancer type, age, sex, chief complaint/examination indication, body mass index, intravenous contrast status, repeat CT examination within 4 weeks, and disposition. Turnaround times from order to the start of the CT examination were calculated. Results The studied group consisted of 267 patients (127 men and 140 women) with a mean age of 56 years and a mean body mass index of 27.8 kg/m 2 . One hundred sixty CT examinations were performed without oral contrast, and 107 CT examinations were performed with oral contrast. There was no significant difference between cases with oral contrast and cases without oral contrast in the number of cases rated as “improved confidence” (odds ratio [OR] 0.54, 95% confidence interval [CI] 0.23–1.31, P  = 0.17), “improved diagnosis” (OR 0.58, 95% CI 0.20–1.64, P  = 0.3), “impaired confidence” (OR 3.92, 95% CI 0.46–33.06, P  = 0.21), or “impaired diagnosis” (OR 2.63, 95% CI 0.29–23.89, P  = 0.39). The turnaround time in the group receiving oral contrast (mean, 141 min; standard deviation, 49.8 min) was significantly longer than that in the group not receiving oral contrast (mean, 109.2 min; standard deviation, 64.8 min) with a mean difference of 31.8 min ( P  
doi_str_mv 10.1007/s00261-017-1175-7
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To the best of our knowledge, oral contrast utility has not previously been specifically assessed in cancer patients presenting to the emergency department. Materials &amp; methods Retrospective review of CT abdomen examinations performed in oncology patients presenting to the emergency department during one month. CT examinations performed with and without oral contrast were rated by two consensus readers for degree of confidence and diagnostic ability. Correlations were assessed for primary cancer type, age, sex, chief complaint/examination indication, body mass index, intravenous contrast status, repeat CT examination within 4 weeks, and disposition. Turnaround times from order to the start of the CT examination were calculated. Results The studied group consisted of 267 patients (127 men and 140 women) with a mean age of 56 years and a mean body mass index of 27.8 kg/m 2 . One hundred sixty CT examinations were performed without oral contrast, and 107 CT examinations were performed with oral contrast. There was no significant difference between cases with oral contrast and cases without oral contrast in the number of cases rated as “improved confidence” (odds ratio [OR] 0.54, 95% confidence interval [CI] 0.23–1.31, P  = 0.17), “improved diagnosis” (OR 0.58, 95% CI 0.20–1.64, P  = 0.3), “impaired confidence” (OR 3.92, 95% CI 0.46–33.06, P  = 0.21), or “impaired diagnosis” (OR 2.63, 95% CI 0.29–23.89, P  = 0.39). The turnaround time in the group receiving oral contrast (mean, 141 min; standard deviation, 49.8 min) was significantly longer than that in the group not receiving oral contrast (mean, 109.2 min; standard deviation, 64.8 min) with a mean difference of 31.8 min ( P  &lt; 0.0001). Conclusion On the basis of our findings and prior studies, targeted rather than default use of oral contrast shows acceptable diagnostic ability in the emergency setting for oncology patients. Benefit from oral contrast use is suggested in scenarios such as suspected fistula/bowel leak/abscess, hypoattenuating peritoneal disease, prior bowel surgery such as gastric bypass, and the absence of intravenous contrast administration. Improvement through the use of targeted oral contrast administration also supports the emergency department need for prompt diagnosis and disposition.</description><identifier>ISSN: 2366-004X</identifier><identifier>EISSN: 2366-0058</identifier><identifier>DOI: 10.1007/s00261-017-1175-7</identifier><identifier>PMID: 28523416</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Abscesses ; Administration, Oral ; Adult ; Body mass ; Body mass index ; Cancer ; Computed tomography ; Confidence intervals ; Contrast Media - administration &amp; dosage ; Diagnosis ; Diagnostic systems ; Emergency medical services ; Emergency Service, Hospital ; Female ; Fistulae ; Gastric bypass ; Gastroenterology ; Hepatology ; Humans ; Imaging ; Intestine ; Intravenous administration ; Male ; Medical diagnosis ; Medicine ; Medicine &amp; Public Health ; Middle Aged ; Neoplasms - diagnostic imaging ; Oncology ; Patients ; Peritoneum ; Radiology ; Readers ; Retrospective Studies ; Standard deviation ; Surgery ; Tomography, X-Ray Computed - methods</subject><ispartof>Abdominal imaging, 2017-11, Vol.42 (11), p.2760-2768</ispartof><rights>Springer Science+Business Media New York 2017</rights><rights>Abdominal Radiology is a copyright of Springer, 2017.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c437t-27ef9bcc1e63b50248fb863beda75b17cb2998f34d3952917211731b955185643</citedby><cites>FETCH-LOGICAL-c437t-27ef9bcc1e63b50248fb863beda75b17cb2998f34d3952917211731b955185643</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00261-017-1175-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00261-017-1175-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,776,780,881,27903,27904,41467,42536,51297</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28523416$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jensen, Corey T.</creatorcontrib><creatorcontrib>Blair, Katherine J.</creatorcontrib><creatorcontrib>Le, Ott</creatorcontrib><creatorcontrib>Sun, Jia</creatorcontrib><creatorcontrib>Wei, Wei</creatorcontrib><creatorcontrib>Korivi, Brinda Rao</creatorcontrib><creatorcontrib>Morani, Ajaykumar C.</creatorcontrib><creatorcontrib>Wagner-Bartak, Nicolaus A.</creatorcontrib><title>Utility of CT oral contrast administration in the emergency department of a quaternary oncology hospital: diagnostic implications, turnaround times, and assessment of ED physician ordering</title><title>Abdominal imaging</title><addtitle>Abdom Radiol</addtitle><addtitle>Abdom Radiol (NY)</addtitle><description>Purpose To compare studies with and without oral contrast on performance of multidetector computed tomography (CT) and the order to CT examination turnaround time in cancer patients presenting to the emergency department (ED). To the best of our knowledge, oral contrast utility has not previously been specifically assessed in cancer patients presenting to the emergency department. Materials &amp; methods Retrospective review of CT abdomen examinations performed in oncology patients presenting to the emergency department during one month. CT examinations performed with and without oral contrast were rated by two consensus readers for degree of confidence and diagnostic ability. Correlations were assessed for primary cancer type, age, sex, chief complaint/examination indication, body mass index, intravenous contrast status, repeat CT examination within 4 weeks, and disposition. Turnaround times from order to the start of the CT examination were calculated. Results The studied group consisted of 267 patients (127 men and 140 women) with a mean age of 56 years and a mean body mass index of 27.8 kg/m 2 . One hundred sixty CT examinations were performed without oral contrast, and 107 CT examinations were performed with oral contrast. There was no significant difference between cases with oral contrast and cases without oral contrast in the number of cases rated as “improved confidence” (odds ratio [OR] 0.54, 95% confidence interval [CI] 0.23–1.31, P  = 0.17), “improved diagnosis” (OR 0.58, 95% CI 0.20–1.64, P  = 0.3), “impaired confidence” (OR 3.92, 95% CI 0.46–33.06, P  = 0.21), or “impaired diagnosis” (OR 2.63, 95% CI 0.29–23.89, P  = 0.39). The turnaround time in the group receiving oral contrast (mean, 141 min; standard deviation, 49.8 min) was significantly longer than that in the group not receiving oral contrast (mean, 109.2 min; standard deviation, 64.8 min) with a mean difference of 31.8 min ( P  &lt; 0.0001). Conclusion On the basis of our findings and prior studies, targeted rather than default use of oral contrast shows acceptable diagnostic ability in the emergency setting for oncology patients. Benefit from oral contrast use is suggested in scenarios such as suspected fistula/bowel leak/abscess, hypoattenuating peritoneal disease, prior bowel surgery such as gastric bypass, and the absence of intravenous contrast administration. 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Public Health</subject><subject>Middle Aged</subject><subject>Neoplasms - diagnostic imaging</subject><subject>Oncology</subject><subject>Patients</subject><subject>Peritoneum</subject><subject>Radiology</subject><subject>Readers</subject><subject>Retrospective Studies</subject><subject>Standard deviation</subject><subject>Surgery</subject><subject>Tomography, X-Ray Computed - methods</subject><issn>2366-004X</issn><issn>2366-0058</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1Uc1u1DAYjBCIVqUPwAVZ4kqKPzuOEw5IaGkBqRKXVuJmOY6TdZXYqT9vpX03Hg6HbVflwMlje2a-nymKt0AvgFL5ESllNZQUZAkgRSlfFKeM13VJqWheHnH166Q4R7yjlEItAJh4XZywRjBeQX1a_L5NbnJpT8JANjckRD0RE3yKGhPR_ey8w3xJLnjiPElbS-xs42i92ZPeLjqm2fq0yjW53-lko9cx23kTpjDuyTbg4pKePpHe6dEHTM4QNy-TM39d8QNJu1UTdr4nyc02v-gMNaJFfDK__EqW7R6dcdrnLnsbnR_fFK8GPaE9fzzPitury5vN9_L657cfmy_Xpam4TCWTdmg7Y8DWvBOUVc3QNRnaXkvRgTQda9tm4FXPW8FakCwvlEPXCgGNqCt-Vnw--C67bra9set-JrVEN-dZVdBO_fvj3VaN4UFlMTBWZ4P3jwYx3O8sJnUX1qEnVNAKYCAbzjMLDiwTA2K0w7ECULVmrg6Zq5y5WjNXMmvePW_tqHhKOBPYgYDLujIbn5X-r-sfHX28Ow</recordid><startdate>20171101</startdate><enddate>20171101</enddate><creator>Jensen, Corey T.</creator><creator>Blair, Katherine J.</creator><creator>Le, Ott</creator><creator>Sun, Jia</creator><creator>Wei, Wei</creator><creator>Korivi, Brinda Rao</creator><creator>Morani, Ajaykumar C.</creator><creator>Wagner-Bartak, Nicolaus A.</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>JQ2</scope><scope>K7-</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>M7Z</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope></search><sort><creationdate>20171101</creationdate><title>Utility of CT oral contrast administration in the emergency department of a quaternary oncology hospital: diagnostic implications, turnaround times, and assessment of ED physician ordering</title><author>Jensen, Corey T. ; 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To the best of our knowledge, oral contrast utility has not previously been specifically assessed in cancer patients presenting to the emergency department. Materials &amp; methods Retrospective review of CT abdomen examinations performed in oncology patients presenting to the emergency department during one month. CT examinations performed with and without oral contrast were rated by two consensus readers for degree of confidence and diagnostic ability. Correlations were assessed for primary cancer type, age, sex, chief complaint/examination indication, body mass index, intravenous contrast status, repeat CT examination within 4 weeks, and disposition. Turnaround times from order to the start of the CT examination were calculated. Results The studied group consisted of 267 patients (127 men and 140 women) with a mean age of 56 years and a mean body mass index of 27.8 kg/m 2 . One hundred sixty CT examinations were performed without oral contrast, and 107 CT examinations were performed with oral contrast. There was no significant difference between cases with oral contrast and cases without oral contrast in the number of cases rated as “improved confidence” (odds ratio [OR] 0.54, 95% confidence interval [CI] 0.23–1.31, P  = 0.17), “improved diagnosis” (OR 0.58, 95% CI 0.20–1.64, P  = 0.3), “impaired confidence” (OR 3.92, 95% CI 0.46–33.06, P  = 0.21), or “impaired diagnosis” (OR 2.63, 95% CI 0.29–23.89, P  = 0.39). The turnaround time in the group receiving oral contrast (mean, 141 min; standard deviation, 49.8 min) was significantly longer than that in the group not receiving oral contrast (mean, 109.2 min; standard deviation, 64.8 min) with a mean difference of 31.8 min ( P  &lt; 0.0001). Conclusion On the basis of our findings and prior studies, targeted rather than default use of oral contrast shows acceptable diagnostic ability in the emergency setting for oncology patients. Benefit from oral contrast use is suggested in scenarios such as suspected fistula/bowel leak/abscess, hypoattenuating peritoneal disease, prior bowel surgery such as gastric bypass, and the absence of intravenous contrast administration. Improvement through the use of targeted oral contrast administration also supports the emergency department need for prompt diagnosis and disposition.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>28523416</pmid><doi>10.1007/s00261-017-1175-7</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
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subjects Abscesses
Administration, Oral
Adult
Body mass
Body mass index
Cancer
Computed tomography
Confidence intervals
Contrast Media - administration & dosage
Diagnosis
Diagnostic systems
Emergency medical services
Emergency Service, Hospital
Female
Fistulae
Gastric bypass
Gastroenterology
Hepatology
Humans
Imaging
Intestine
Intravenous administration
Male
Medical diagnosis
Medicine
Medicine & Public Health
Middle Aged
Neoplasms - diagnostic imaging
Oncology
Patients
Peritoneum
Radiology
Readers
Retrospective Studies
Standard deviation
Surgery
Tomography, X-Ray Computed - methods
title Utility of CT oral contrast administration in the emergency department of a quaternary oncology hospital: diagnostic implications, turnaround times, and assessment of ED physician ordering
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