NMDA receptors: linking physiological output to biophysical operation

Key Points NMDA receptor isoforms respond to glutamate with distinct kinetics and have dynamic, complex and incompletely delineated expression profiles; precise mechanistic information for specific receptor isoforms is derived from recombinant preparations. Functional attributes of recombinant recep...

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Veröffentlicht in:	Nature reviews. Neuroscience 2017-04, Vol.18 (4), p.236-249
Hauptverfasser:	Iacobucci, Gary J., Popescu, Gabriela K.
Format:	Artikel
Sprache:	eng
Schlagworte:	13/106 13/109 631/378/548/1964 692/698/1688/1366/64 82/80 9/30 9/74 9/97 96/95 Animal Genetics and Genomics Animals Behavioral Sciences Biological Techniques Biomedicine Cell receptors Cellular signal transduction Genetic aspects Glutamic Acid - physiology Humans Kinetics Localization (Brain function) Models, Neurological Neurobiology Neurosciences Physiology Psychological aspects Receptors, N-Methyl-D-Aspartate - physiology review-article Synaptic Transmission - physiology
Online-Zugang:	Volltext
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