Severe Hemorrhagic Shock Leads to a Delayed Fracture Healing and Decreased Bone Callus Strength in a Mouse Model

Background Multiple trauma is frequently associated with hemorrhagic shock and fractures of the extremities. Clinically, the rate of impaired fracture healing (delayed healing and nonunion) seems to be increased in patients with multiple injuries compared with patients with isolated fractures. As th...

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Veröffentlicht in:	Clinical orthopaedics and related research 2017-11, Vol.475 (11), p.2783-2794
Hauptverfasser:	Bundkirchen, Katrin, Macke, Christian, Reifenrath, Janin, Schäck, Luisa Marilena, Noack, Sandra, Relja, Borna, Naber, Philipp, Welke, Bastian, Fehr, Michael, Krettek, Christian, Neunaber, Claudia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Basic Research Biomechanical Phenomena Bone density Bone healing Bone mass Bones Bony Callus - diagnostic imaging Bony Callus - physiopathology Callus Catheters Conservative Orthopedics Disease Models, Animal Femoral Fractures - complications Femoral Fractures - diagnostic imaging Femoral Fractures - physiopathology Femur Fracture Healing Fractures Hemorrhage Male Mechanical properties Medicine Medicine & Public Health Mice, Inbred C57BL Nonunion Orthopedics Osteotomy Radiography Risk Factors Shock Shock, Hemorrhagic - complications Sports Medicine Surgery Surgical Orthopedics Time Factors Trauma X-Ray Microtomography
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