Prefrontal Connectivity & Glutamate Transmission: Relevance to Depression Pathophysiology and Ketamine Treatment

Abstract Background Prefrontal global brain connectivity with global signal regression (GBCr) was proposed as a robust biomarker of depression, and was associated with ketamine’s mechanism of action. Here, we investigated prefrontal GBCr in treatment-resistant depression (TRD) at baseline and follow...

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Veröffentlicht in:	Biological psychiatry : cognitive neuroscience and neuroimaging 2017-10, Vol.2 (7), p.566-574
Hauptverfasser:	Abdallah, Chadi G., M.D, Averill, Christopher L., B.S, Salas, Ramiro, Ph.D, Averill, Lynnette A., Ph.D, Baldwin, Philip R., Ph.D, Krystal, John H., M.D, Mathew, Sanjay J., M.D, Mathalon, Daniel H., Ph.D., M.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Functional MRI Global brain connectivity Glutamate Ketamine Psychiatry Rapid-acting antidepressants Treatment-resistant depression
Online-Zugang:	Volltext
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