Pharmacokinetics (PK) and Safety of Intravenous (IV) Brincidofovir (BCV) in Healthy Adult Subjects

Abstract Background BCV is a lipid conjugate nucleotide that has shown rapid viral clearance in patients with adenovirus infection and improved survival in animal models of smallpox. In preclinical studies in rats, IV BCV dosed twice weekly for up to 29 days was not associated with gastrointestinal...

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Veröffentlicht in:Open forum infectious diseases 2017-10, Vol.4 (suppl_1), p.S311-S311
Hauptverfasser: Wire, Mary Beth, Morrison, Marion, Anderson, Maggie, Arumugham, Thangam, Dunn, John, Naderer, Odin
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Sprache:eng
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