The Molecular Chaperone DnaK Is a Source of Mutational Robustness

Molecular chaperones, also known as heat-shock proteins, refold misfolded proteins and help other proteins reach their native conformation. Thanks to these abilities, some chaperones, such as the Hsp90 protein or the chaperonin GroEL, can buffer the deleterious phenotypic effects of mutations that a...

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Veröffentlicht in:	Genome biology and evolution 2016-09, Vol.8 (9), p.2979-2991
Hauptverfasser:	Aguilar-Rodríguez, José, Sabater-Muñoz, Beatriz, Montagud-Martínez, Roser, Berlanga, Víctor, Alvarez-Ponce, David, Wagner, Andreas, Fares, Mario A
Format:	Artikel
Sprache:	eng
Schlagworte:	Escherichia coli - genetics Escherichia coli Proteins - genetics Escherichia coli Proteins - metabolism HSP70 Heat-Shock Proteins - genetics HSP70 Heat-Shock Proteins - metabolism Mutation Rate Point Mutation
Online-Zugang:	Volltext
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