A cellular platform for the evaluation of immune checkpoint molecules

Blockade of the T cell coinhibitory molecules CTLA-4 and PD-1 has clinical utility to strengthen T cell responses. In addition to these immune checkpoints an ever-growing number of molecules has been implicated in generating coinhibitory signals in T cells. However, investigating coinhibitory molecu...

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Veröffentlicht in:	Oncotarget 2017-09, Vol.8 (39), p.64892-64906
Hauptverfasser:	Jutz, Sabrina, Hennig, Annika, Paster, Wolfgang, Asrak, Ömer, Dijanovic, Dejana, Kellner, Florian, Pickl, Winfried F, Huppa, Johannes B, Leitner, Judith, Steinberger, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Research Paper: Immunology
Online-Zugang:	Volltext
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