Development and validation of a risk stratification model for prediction of disability and hospitalisation in patients with heart failure: a study protocol
BackgroundChronic heart failure (CHF) reduces quality of life and causes hospitalisation and death. Identifying predictive factors of such events may help change the natural history of this condition.AimTo develop and validate a stratification system for classifying patients with CHF, according to t...
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| creator | García-Olmos, Luis Rodríguez-Salvanés, Francisco Batlle-Pérez, Maurice Aguilar-Torres, Río Porro-Fernández, Carlos García-Cabello, Alfredo Carmona, Montserrat Ruiz-Alonso, Sergio Garrido-Elustondo, Sofía Alberquilla, Ángel Sánchez-Gómez, Luis María Sánchez de Madariaga, Ricardo Monge-Navarrete, Elena Benito-Ortiz, Luis Baños-Pérez, Nicolás Simón-Puerta, Amaya López Rodríguez, Ana Belén Martínez-Álvarez, Miguel Ángel Velilla-Celma, María Ángeles Bernal-Gómez, María Isabel |
| description | BackgroundChronic heart failure (CHF) reduces quality of life and causes hospitalisation and death. Identifying predictive factors of such events may help change the natural history of this condition.AimTo develop and validate a stratification system for classifying patients with CHF, according to their degree of disability and need for hospitalisation due to any unscheduled cause, over a period of 1 year.Methods and analysisProspective, concurrent, cohort-type study in two towns in the Madrid autonomous region having a combined population of 1 32 851. The study will include patients aged over 18 years who meet the following diagnostic criteria: symptoms and typical signs of CHF (Framingham criteria) and left ventricular ejection fraction (EF)50%).Outcome variables will be(a) Disability, as measured by the WHO Disability Assessment Schedule V.2.0 Questionnaire, and (b) unscheduled hospitalisations. The estimated sample size is 557 patients, 371 for predictive model development (development cohort) and 186 for validation purposes (validation cohort). Predictive models of disability or hospitalisation will be constructed using logistic regression techniques. The resulting model(s) will be validated by estimating the probability of outcomes of interest for each individual included in the validation cohort.Ethics and disseminationThe study protocol has been approved by the Clinical Research Ethics Committee of La Princesa University Teaching Hospital (PI-705). All results will be published in a peer-reviewed journal and shared with the medical community at conferences and scientific meetings. |
| doi_str_mv | 10.1136/bmjopen-2016-014840 |
| format | Article |
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Identifying predictive factors of such events may help change the natural history of this condition.AimTo develop and validate a stratification system for classifying patients with CHF, according to their degree of disability and need for hospitalisation due to any unscheduled cause, over a period of 1 year.Methods and analysisProspective, concurrent, cohort-type study in two towns in the Madrid autonomous region having a combined population of 1 32 851. The study will include patients aged over 18 years who meet the following diagnostic criteria: symptoms and typical signs of CHF (Framingham criteria) and left ventricular ejection fraction (EF)<50% or structural cardiac lesion and/or diastolic dysfunction in the presence of preserved EF (EF>50%).Outcome variables will be(a) Disability, as measured by the WHO Disability Assessment Schedule V.2.0 Questionnaire, and (b) unscheduled hospitalisations. The estimated sample size is 557 patients, 371 for predictive model development (development cohort) and 186 for validation purposes (validation cohort). Predictive models of disability or hospitalisation will be constructed using logistic regression techniques. The resulting model(s) will be validated by estimating the probability of outcomes of interest for each individual included in the validation cohort.Ethics and disseminationThe study protocol has been approved by the Clinical Research Ethics Committee of La Princesa University Teaching Hospital (PI-705). All results will be published in a peer-reviewed journal and shared with the medical community at conferences and scientific meetings.</description><identifier>ISSN: 2044-6055</identifier><identifier>EISSN: 2044-6055</identifier><identifier>DOI: 10.1136/bmjopen-2016-014840</identifier><identifier>PMID: 28600367</identifier><language>eng</language><publisher>England: BMJ Publishing Group LTD</publisher><subject>Activities of daily living ; Aged ; Aged, 80 and over ; Chronic Disease ; Chronic illnesses ; Chronic obstructive pulmonary disease ; Comorbidity ; Disability Evaluation ; Female ; General practice / Family practice ; Heart failure ; Heart Failure - diagnosis ; Hospitalization ; Hospitalization - statistics & numerical data ; Humans ; Male ; Medical prognosis ; Middle Aged ; Mortality ; Patient admissions ; Polypharmacy ; Population ; Predictive Value of Tests ; Primary care ; Prospective Studies ; Publishing ; Risk Assessment - methods ; Risk Factors ; Sociodemographics ; Socioeconomic factors ; Spain ; Systematic review</subject><ispartof>BMJ open, 2017-06, Vol.7 (6), p.e014840</ispartof><rights>Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.</rights><rights>2017 Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b500t-4bc4d21965c333b95aabee77ab086d9d1b15109ff5069ce42f4c583e17340ea13</citedby><cites>FETCH-LOGICAL-b500t-4bc4d21965c333b95aabee77ab086d9d1b15109ff5069ce42f4c583e17340ea13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://bmjopen.bmj.com/content/7/6/e014840.full.pdf$$EPDF$$P50$$Gbmj$$Hfree_for_read</linktopdf><linktohtml>$$Uhttp://bmjopen.bmj.com/content/7/6/e014840.full$$EHTML$$P50$$Gbmj$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,861,882,27530,27531,27905,27906,53772,53774,77350,77381</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28600367$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>García-Olmos, Luis</creatorcontrib><creatorcontrib>Rodríguez-Salvanés, Francisco</creatorcontrib><creatorcontrib>Batlle-Pérez, Maurice</creatorcontrib><creatorcontrib>Aguilar-Torres, Río</creatorcontrib><creatorcontrib>Porro-Fernández, Carlos</creatorcontrib><creatorcontrib>García-Cabello, Alfredo</creatorcontrib><creatorcontrib>Carmona, Montserrat</creatorcontrib><creatorcontrib>Ruiz-Alonso, Sergio</creatorcontrib><creatorcontrib>Garrido-Elustondo, Sofía</creatorcontrib><creatorcontrib>Alberquilla, Ángel</creatorcontrib><creatorcontrib>Sánchez-Gómez, Luis María</creatorcontrib><creatorcontrib>Sánchez de Madariaga, Ricardo</creatorcontrib><creatorcontrib>Monge-Navarrete, Elena</creatorcontrib><creatorcontrib>Benito-Ortiz, Luis</creatorcontrib><creatorcontrib>Baños-Pérez, Nicolás</creatorcontrib><creatorcontrib>Simón-Puerta, Amaya</creatorcontrib><creatorcontrib>López Rodríguez, Ana Belén</creatorcontrib><creatorcontrib>Martínez-Álvarez, Miguel Ángel</creatorcontrib><creatorcontrib>Velilla-Celma, María Ángeles</creatorcontrib><creatorcontrib>Bernal-Gómez, María Isabel</creatorcontrib><creatorcontrib>CHIC Group</creatorcontrib><title>Development and validation of a risk stratification model for prediction of disability and hospitalisation in patients with heart failure: a study protocol</title><title>BMJ open</title><addtitle>BMJ Open</addtitle><description>BackgroundChronic heart failure (CHF) reduces quality of life and causes hospitalisation and death. Identifying predictive factors of such events may help change the natural history of this condition.AimTo develop and validate a stratification system for classifying patients with CHF, according to their degree of disability and need for hospitalisation due to any unscheduled cause, over a period of 1 year.Methods and analysisProspective, concurrent, cohort-type study in two towns in the Madrid autonomous region having a combined population of 1 32 851. The study will include patients aged over 18 years who meet the following diagnostic criteria: symptoms and typical signs of CHF (Framingham criteria) and left ventricular ejection fraction (EF)<50% or structural cardiac lesion and/or diastolic dysfunction in the presence of preserved EF (EF>50%).Outcome variables will be(a) Disability, as measured by the WHO Disability Assessment Schedule V.2.0 Questionnaire, and (b) unscheduled hospitalisations. The estimated sample size is 557 patients, 371 for predictive model development (development cohort) and 186 for validation purposes (validation cohort). Predictive models of disability or hospitalisation will be constructed using logistic regression techniques. The resulting model(s) will be validated by estimating the probability of outcomes of interest for each individual included in the validation cohort.Ethics and disseminationThe study protocol has been approved by the Clinical Research Ethics Committee of La Princesa University Teaching Hospital (PI-705). All results will be published in a peer-reviewed journal and shared with the medical community at conferences and scientific meetings.</description><subject>Activities of daily living</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Chronic Disease</subject><subject>Chronic illnesses</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Comorbidity</subject><subject>Disability Evaluation</subject><subject>Female</subject><subject>General practice / Family practice</subject><subject>Heart failure</subject><subject>Heart Failure - diagnosis</subject><subject>Hospitalization</subject><subject>Hospitalization - statistics & numerical data</subject><subject>Humans</subject><subject>Male</subject><subject>Medical prognosis</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Patient admissions</subject><subject>Polypharmacy</subject><subject>Population</subject><subject>Predictive Value of Tests</subject><subject>Primary care</subject><subject>Prospective Studies</subject><subject>Publishing</subject><subject>Risk Assessment - methods</subject><subject>Risk Factors</subject><subject>Sociodemographics</subject><subject>Socioeconomic factors</subject><subject>Spain</subject><subject>Systematic review</subject><issn>2044-6055</issn><issn>2044-6055</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>9YT</sourceid><sourceid>ACMMV</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqNks9u1DAQxiMEolXpEyAhS1y4pPh_Eg5IqNCCVIkLnC3HnrBenDjYzlb7LLwsXrKtCgeELx55vvnNjPxV1XOCLwhh8nU_bsMMU00xkTUmvOX4UXVKMee1xEI8fhCfVOcpbXE5XHRC0KfVCW0lxkw2p9XP97ADH-YRpoz0ZNFOe2d1dmFCYUAaRZe-o5RjeRqcWRNjsODRECKaI1hn7tTWJd077_L-N2oT0uxy4aW1zE1oLlHplNCtyxu0AR0zGrTzS4Q3pVnKi90XaMjBBP-sejJon-D8eJ9VX68-fLn8WN98vv50-e6m7gXGuea94ZaSTgrDGOs7oXUP0DS6x620nSU9EQR3wyCw7AxwOnAjWgakYRyDJuyserty56UfwZoyYNRezdGNOu5V0E79mZncRn0LOyUkZYx3BfDqCIjhxwIpq9ElA97rCcKSFOlwy2nb4KZIX_4l3YYlTmU9RaXkpCm_RP-lKqyGUt7Qw9xsVZkYUoow3I9MsDq4RB1dog4uUatLStWLh9ve19x5ogguVkGp_i_iL5qIzAY</recordid><startdate>20170601</startdate><enddate>20170601</enddate><creator>García-Olmos, Luis</creator><creator>Rodríguez-Salvanés, Francisco</creator><creator>Batlle-Pérez, Maurice</creator><creator>Aguilar-Torres, Río</creator><creator>Porro-Fernández, Carlos</creator><creator>García-Cabello, Alfredo</creator><creator>Carmona, Montserrat</creator><creator>Ruiz-Alonso, Sergio</creator><creator>Garrido-Elustondo, Sofía</creator><creator>Alberquilla, Ángel</creator><creator>Sánchez-Gómez, Luis María</creator><creator>Sánchez de Madariaga, Ricardo</creator><creator>Monge-Navarrete, Elena</creator><creator>Benito-Ortiz, Luis</creator><creator>Baños-Pérez, Nicolás</creator><creator>Simón-Puerta, Amaya</creator><creator>López Rodríguez, Ana Belén</creator><creator>Martínez-Álvarez, Miguel Ángel</creator><creator>Velilla-Celma, María Ángeles</creator><creator>Bernal-Gómez, María Isabel</creator><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>9YT</scope><scope>ACMMV</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20170601</creationdate><title>Development and validation of a risk stratification model for prediction of disability and hospitalisation in patients with heart failure: a study protocol</title><author>García-Olmos, Luis ; Rodríguez-Salvanés, Francisco ; Batlle-Pérez, Maurice ; Aguilar-Torres, Río ; Porro-Fernández, Carlos ; García-Cabello, Alfredo ; Carmona, Montserrat ; Ruiz-Alonso, Sergio ; Garrido-Elustondo, Sofía ; Alberquilla, Ángel ; Sánchez-Gómez, Luis María ; Sánchez de Madariaga, Ricardo ; Monge-Navarrete, Elena ; Benito-Ortiz, Luis ; Baños-Pérez, Nicolás ; Simón-Puerta, Amaya ; López Rodríguez, Ana Belén ; Martínez-Álvarez, Miguel Ángel ; Velilla-Celma, María Ángeles ; Bernal-Gómez, María Isabel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b500t-4bc4d21965c333b95aabee77ab086d9d1b15109ff5069ce42f4c583e17340ea13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Activities of daily living</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Chronic Disease</topic><topic>Chronic illnesses</topic><topic>Chronic obstructive pulmonary disease</topic><topic>Comorbidity</topic><topic>Disability Evaluation</topic><topic>Female</topic><topic>General practice / Family practice</topic><topic>Heart failure</topic><topic>Heart Failure - diagnosis</topic><topic>Hospitalization</topic><topic>Hospitalization - statistics & numerical data</topic><topic>Humans</topic><topic>Male</topic><topic>Medical prognosis</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Patient admissions</topic><topic>Polypharmacy</topic><topic>Population</topic><topic>Predictive Value of Tests</topic><topic>Primary care</topic><topic>Prospective Studies</topic><topic>Publishing</topic><topic>Risk Assessment - methods</topic><topic>Risk Factors</topic><topic>Sociodemographics</topic><topic>Socioeconomic factors</topic><topic>Spain</topic><topic>Systematic review</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>García-Olmos, Luis</creatorcontrib><creatorcontrib>Rodríguez-Salvanés, Francisco</creatorcontrib><creatorcontrib>Batlle-Pérez, Maurice</creatorcontrib><creatorcontrib>Aguilar-Torres, Río</creatorcontrib><creatorcontrib>Porro-Fernández, Carlos</creatorcontrib><creatorcontrib>García-Cabello, Alfredo</creatorcontrib><creatorcontrib>Carmona, Montserrat</creatorcontrib><creatorcontrib>Ruiz-Alonso, Sergio</creatorcontrib><creatorcontrib>Garrido-Elustondo, Sofía</creatorcontrib><creatorcontrib>Alberquilla, Ángel</creatorcontrib><creatorcontrib>Sánchez-Gómez, Luis María</creatorcontrib><creatorcontrib>Sánchez de Madariaga, Ricardo</creatorcontrib><creatorcontrib>Monge-Navarrete, Elena</creatorcontrib><creatorcontrib>Benito-Ortiz, Luis</creatorcontrib><creatorcontrib>Baños-Pérez, Nicolás</creatorcontrib><creatorcontrib>Simón-Puerta, Amaya</creatorcontrib><creatorcontrib>López Rodríguez, Ana Belén</creatorcontrib><creatorcontrib>Martínez-Álvarez, Miguel Ángel</creatorcontrib><creatorcontrib>Velilla-Celma, María Ángeles</creatorcontrib><creatorcontrib>Bernal-Gómez, María Isabel</creatorcontrib><creatorcontrib>CHIC Group</creatorcontrib><collection>BMJ Open Access Journals</collection><collection>BMJ Journals:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Nursing & Allied Health Premium</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMJ open</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>García-Olmos, Luis</au><au>Rodríguez-Salvanés, Francisco</au><au>Batlle-Pérez, Maurice</au><au>Aguilar-Torres, Río</au><au>Porro-Fernández, Carlos</au><au>García-Cabello, Alfredo</au><au>Carmona, Montserrat</au><au>Ruiz-Alonso, Sergio</au><au>Garrido-Elustondo, Sofía</au><au>Alberquilla, Ángel</au><au>Sánchez-Gómez, Luis María</au><au>Sánchez de Madariaga, Ricardo</au><au>Monge-Navarrete, Elena</au><au>Benito-Ortiz, Luis</au><au>Baños-Pérez, Nicolás</au><au>Simón-Puerta, Amaya</au><au>López Rodríguez, Ana Belén</au><au>Martínez-Álvarez, Miguel Ángel</au><au>Velilla-Celma, María Ángeles</au><au>Bernal-Gómez, María Isabel</au><aucorp>CHIC Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Development and validation of a risk stratification model for prediction of disability and hospitalisation in patients with heart failure: a study protocol</atitle><jtitle>BMJ open</jtitle><addtitle>BMJ Open</addtitle><date>2017-06-01</date><risdate>2017</risdate><volume>7</volume><issue>6</issue><spage>e014840</spage><pages>e014840-</pages><issn>2044-6055</issn><eissn>2044-6055</eissn><abstract>BackgroundChronic heart failure (CHF) reduces quality of life and causes hospitalisation and death. Identifying predictive factors of such events may help change the natural history of this condition.AimTo develop and validate a stratification system for classifying patients with CHF, according to their degree of disability and need for hospitalisation due to any unscheduled cause, over a period of 1 year.Methods and analysisProspective, concurrent, cohort-type study in two towns in the Madrid autonomous region having a combined population of 1 32 851. The study will include patients aged over 18 years who meet the following diagnostic criteria: symptoms and typical signs of CHF (Framingham criteria) and left ventricular ejection fraction (EF)<50% or structural cardiac lesion and/or diastolic dysfunction in the presence of preserved EF (EF>50%).Outcome variables will be(a) Disability, as measured by the WHO Disability Assessment Schedule V.2.0 Questionnaire, and (b) unscheduled hospitalisations. The estimated sample size is 557 patients, 371 for predictive model development (development cohort) and 186 for validation purposes (validation cohort). Predictive models of disability or hospitalisation will be constructed using logistic regression techniques. The resulting model(s) will be validated by estimating the probability of outcomes of interest for each individual included in the validation cohort.Ethics and disseminationThe study protocol has been approved by the Clinical Research Ethics Committee of La Princesa University Teaching Hospital (PI-705). All results will be published in a peer-reviewed journal and shared with the medical community at conferences and scientific meetings.</abstract><cop>England</cop><pub>BMJ Publishing Group LTD</pub><pmid>28600367</pmid><doi>10.1136/bmjopen-2016-014840</doi><oa>free_for_read</oa></addata></record> |
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| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5623349 |
| source | BMJ Open Access Journals; MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; PubMed Central |
| subjects | Activities of daily living Aged Aged, 80 and over Chronic Disease Chronic illnesses Chronic obstructive pulmonary disease Comorbidity Disability Evaluation Female General practice / Family practice Heart failure Heart Failure - diagnosis Hospitalization Hospitalization - statistics & numerical data Humans Male Medical prognosis Middle Aged Mortality Patient admissions Polypharmacy Population Predictive Value of Tests Primary care Prospective Studies Publishing Risk Assessment - methods Risk Factors Sociodemographics Socioeconomic factors Spain Systematic review |
| title | Development and validation of a risk stratification model for prediction of disability and hospitalisation in patients with heart failure: a study protocol |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T13%3A34%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Development%20and%20validation%20of%20a%20risk%20stratification%20model%20for%20prediction%20of%20disability%20and%20hospitalisation%20in%20patients%20with%20heart%20failure:%20a%20study%20protocol&rft.jtitle=BMJ%20open&rft.au=Garc%C3%ADa-Olmos,%20Luis&rft.aucorp=CHIC%20Group&rft.date=2017-06-01&rft.volume=7&rft.issue=6&rft.spage=e014840&rft.pages=e014840-&rft.issn=2044-6055&rft.eissn=2044-6055&rft_id=info:doi/10.1136/bmjopen-2016-014840&rft_dat=%3Cproquest_pubme%3E1908428707%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1907224721&rft_id=info:pmid/28600367&rfr_iscdi=true |