Adrenergic-mediated increases in INHBA drive CAF phenotype and collagens

Adrenergic signaling is known to promote tumor growth and metastasis, but the effects on tumor stroma are not well understood. An unbiased bioinformatics approach analyzing tumor samples from patients with known biobehavioral profiles identified a prominent stromal signature associated with cancer-a...

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Veröffentlicht in:	JCI insight 2017-08, Vol.2 (16)
Hauptverfasser:	Nagaraja, Archana S, Dood, Robert L, Armaiz-Pena, Guillermo, Kang, Yu, Wu, Sherry Y, Allen, Julie K, Jennings, Nicholas B, Mangala, Lingegowda S, Pradeep, Sunila, Lyons, Yasmin, Haemmerle, Monika, Gharpure, Kshipra M, Sadaoui, Nouara C, Rodriguez-Aguayo, Cristian, Ivan, Cristina, Wang, Ying, Baggerly, Keith, Ram, Prahlad, Lopez-Berestein, Gabriel, Liu, Jinsong, Mok, Samuel C, Cohen, Lorenzo, Lutgendorf, Susan K, Cole, Steve W, Sood, Anil K
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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