Age-related Impairment of Vascular Structure and Functions
Among age-related diseases, cardiovascular and cerebrovascular diseases are major causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age is an independent and essential risk factor. The present work will review morphological alterations of aging vessels in-depth,...
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| Veröffentlicht in: | Aging and disease 2017-10, Vol.8 (5), p.590-610 |
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| container_issue | 5 |
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| container_title | Aging and disease |
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| creator | Xu, Xianglai Wang, Brian Ren, Changhong Hu, Jiangnan Greenberg, David A Chen, Tianxiang Xie, Liping Jin, Kunlin |
| description | Among age-related diseases, cardiovascular and cerebrovascular diseases are major causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age is an independent and essential risk factor. The present work will review morphological alterations of aging vessels in-depth, which includes the discussion of age-related microvessel loss and changes to vasculature involving the capillary basement membrane, intima, media, and adventitia as well as the accompanying vascular dysfunctions arising from these alterations. |
| doi_str_mv | 10.14336/ad.2017.0430 |
| format | Article |
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| language | eng |
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| source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Aging (Biology) Cardiovascular diseases Health aspects Review Risk factors |
| title | Age-related Impairment of Vascular Structure and Functions |
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