Parity History Determines a Systemic Inflammatory Response to Spread of Ovarian Cancer in Naturally Aged Mice

Aging intersects with reproductive senescence in women by promoting a systemic low-grade chronic inflammation that predisposes women to several diseases including ovarian cancer (OC). OC risk at menopause is significantly modified by parity records during prior fertile life. To date, the combined ef...

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Veröffentlicht in:Aging and disease 2017-10, Vol.8 (5), p.546-557
Hauptverfasser: Urzua, Ulises, Chacon, Carlos, Lizama, Luis, Sarmiento, Sebastián, Villalobos, Pía, Kroxato, Belén, Marcelain, Katherine, Gonzalez, María-Julieta
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Sprache:eng
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