Perivascular adipose tissue inflammation in vascular disease

Perivascular adipose tissue (PVAT) plays a critical role in the pathogenesis of cardiovascular disease. In vascular pathologies, perivascular adipose tissue increases in volume and becomes dysfunctional, with altered cellular composition and molecular characteristics. PVAT dysfunction is characteriz...

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Veröffentlicht in:	British journal of pharmacology 2017-10, Vol.174 (20), p.3496-3513
Hauptverfasser:	Nosalski, Ryszard, Guzik, Tomasz J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adiponectin Adipose tissue Adipose Tissue - physiopathology Animals Arteriosclerosis Beta cells Bioavailability Blood Vessels - physiopathology Chemokines Cytokines - physiology Dendritic cells Diabetes mellitus Endothelium Fibroblasts Humans Inflammation Inflammation - immunology Inflammation - physiopathology Interleukin 17 Interleukin 6 Leptin Lymphocytes Lymphocytes T Macrophages Molecular modelling Monocyte chemoattractant protein 1 Muscles NAD(P)H oxidase Oxidative stress Paracrine signalling RANTES Review Smooth muscle Structure-function relationships Superoxide Themed Section: Review Vascular Diseases - immunology Vascular Diseases - physiopathology
Online-Zugang:	Volltext
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