HLA imputation in an admixed population: An assessment of the 1000 Genomes data as a training set

Abstract Methods to impute HLA alleles based on dense single nucleotide polymorphism (SNP) data provide a valuable resource to association studies and evolutionary investigation of the MHC region. The availability of appropriate training sets is critical to the accuracy of HLA imputation, and the in...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Human immunology 2016-03, Vol.77 (3), p.307-312
Hauptverfasser:	Nunes, Kelly, Zheng, Xiuwen, Torres, Margareth, Moraes, Maria Elisa, Piovezan, Bruno Z, Pontes, Gerlandia N, Kimura, Lilian, Carnavalli, Juliana E.P, Mingroni Netto, Regina C, Meyer, Diogo
Format:	Artikel
Sprache:	eng
Schlagworte:	1000 Genomes Admixed populations Alleles Allergy and Immunology Brazil Computational Biology - methods Databases, Genetic Genetics, Population Genome, Human Genome-Wide Association Study HLA HLA Antigens - genetics Humans Imputation Polymorphism, Single Nucleotide Relatedness Reproducibility of Results Software Web Browser
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!