Mechanical microenvironments and protein expression associated with formation of different skeletal tissues during bone healing

Uncovering the mechanisms of the sensitivity of bone healing to mechanical factors is critical for understanding the basic biology and mechanobiology of the skeleton, as well as for enhancing clinical treatment of bone injuries. This study refined an experimental method of measuring the strain micro...

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Veröffentlicht in:	Biomechanics and modeling in mechanobiology 2015-11, Vol.14 (6), p.1239-1253
Hauptverfasser:	Miller, Gregory J., Gerstenfeld, Louis C., Morgan, Elise F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and Medical Physics Biomechanics Biomedical Engineering and Bioengineering Biophysics Bone Regeneration Bones Cartilage Cellular Microenvironment - physiology Computer Simulation Elastic Modulus Engineering Experimental methods Extracellular Matrix - physiology Extracellular Matrix Proteins - physiology Femoral Fractures - physiopathology Formations Fracture Healing - physiology Gene Expression Regulation Healing Injuries Kinases Male Mechanotransduction, Cellular Microenvironments Models, Biological Original Paper Protein expression Proteins Rats Rats, Sprague-Dawley Strain Stress, Mechanical Theoretical and Applied Mechanics Tissues
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