Laryngeal paracoccidioidomycosis presenting as solitary true vocal fold disease
Paracoccidioidomycosis (PCM) is a systemic granulomatous disease caused by Paracoccidioides brasiliensis or P. lutzii. It is a neglected tropical infectious disease that poses a major public health burden in endemic areas of Latin America. Mucosae of the upper digestive and respiratory tracts are co...
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creator | Eyer-Silva, Walter de Araujo Santana, Annelise Callmann Silva, Guilherme Almeida Rosa da Azevedo, Marcelo Costa Velho Mendes de Barreto, Juliana Li Ting Matos Sun Neumann, Marina Apolloni Castro, Izana Junqueira de Basílio-de-Oliveira, Rodrigo Panno Araujo, Luciana Ferreira de Ré, Nathane Zanineli Oliveira, Felipe Marques de Simas, Caio José de Araujo Sarvat, Marcos André de Ferry, Fernando Raphael de Almeida |
description | Paracoccidioidomycosis (PCM) is a systemic granulomatous disease caused by Paracoccidioides brasiliensis or P. lutzii. It is a neglected tropical infectious disease that poses a major public health burden in endemic areas of Latin America. Mucosae of the upper digestive and respiratory tracts are commonly involved and many patients have disease at multiple mucosal sites, with or without lung involvement. Mucosal PCM presenting as solitary true vocal fold disease is relatively rare. We present the case of a 67-year-old Brazilian forest guard who presented with a 6-month history of hoarseness and globus pharyngeus due to a solitary left true vocal fold infiltration and vegetation diagnosed as PCM. Silent pulmonary disease was also present. A laryngoscopy video is offered as supplemental material to this report. He completely remitted after surgical removal and amphotericin B deoxycholate treatment. |
doi_str_mv | 10.1016/j.idcr.2017.09.003 |
format | Article |
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It is a neglected tropical infectious disease that poses a major public health burden in endemic areas of Latin America. Mucosae of the upper digestive and respiratory tracts are commonly involved and many patients have disease at multiple mucosal sites, with or without lung involvement. Mucosal PCM presenting as solitary true vocal fold disease is relatively rare. We present the case of a 67-year-old Brazilian forest guard who presented with a 6-month history of hoarseness and globus pharyngeus due to a solitary left true vocal fold infiltration and vegetation diagnosed as PCM. Silent pulmonary disease was also present. A laryngoscopy video is offered as supplemental material to this report. He completely remitted after surgical removal and amphotericin B deoxycholate treatment.</description><identifier>ISSN: 2214-2509</identifier><identifier>EISSN: 2214-2509</identifier><identifier>DOI: 10.1016/j.idcr.2017.09.003</identifier><identifier>PMID: 28966914</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Case Report ; Laryngeal ; Paracoccidioidomycosis ; South American blastomycosis ; Vocal cord ; Vocal fold</subject><ispartof>IDCases, 2017-01, Vol.10, p.71-74</ispartof><rights>2017 The Authors</rights><rights>2017 The Authors 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c406t-5afa2dab2f0d27d9bcacaf8dd9f522244064a0f4546a899bfc366418980dba6d3</cites><orcidid>0000-0003-3107-1461 ; 0000-0003-0802-2418 ; 0000-0002-5407-9653 ; 0000-0002-4239-9174 ; 0000-0002-1979-0204 ; 0000-0003-4476-2341 ; 0000-0002-8296-6516 ; 0000-0002-1727-0950 ; 0000-0001-6386-666X ; 0000-0002-2119-310X ; 0000-0001-6323-4961 ; 0000-0002-6848-2857 ; 0000-0002-1881-0437 ; 0000-0001-7859-226X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608563/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608563/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,861,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28966914$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Eyer-Silva, Walter de Araujo</creatorcontrib><creatorcontrib>Santana, Annelise Callmann</creatorcontrib><creatorcontrib>Silva, Guilherme Almeida Rosa da</creatorcontrib><creatorcontrib>Azevedo, Marcelo Costa Velho Mendes de</creatorcontrib><creatorcontrib>Barreto, Juliana Li Ting Matos Sun</creatorcontrib><creatorcontrib>Neumann, Marina Apolloni</creatorcontrib><creatorcontrib>Castro, Izana Junqueira de</creatorcontrib><creatorcontrib>Basílio-de-Oliveira, Rodrigo Panno</creatorcontrib><creatorcontrib>Araujo, Luciana Ferreira de</creatorcontrib><creatorcontrib>Ré, Nathane Zanineli</creatorcontrib><creatorcontrib>Oliveira, Felipe Marques de</creatorcontrib><creatorcontrib>Simas, Caio José de Araujo</creatorcontrib><creatorcontrib>Sarvat, Marcos André de</creatorcontrib><creatorcontrib>Ferry, Fernando Raphael de Almeida</creatorcontrib><title>Laryngeal paracoccidioidomycosis presenting as solitary true vocal fold disease</title><title>IDCases</title><addtitle>IDCases</addtitle><description>Paracoccidioidomycosis (PCM) is a systemic granulomatous disease caused by Paracoccidioides brasiliensis or P. lutzii. 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subjects | Case Report Laryngeal Paracoccidioidomycosis South American blastomycosis Vocal cord Vocal fold |
title | Laryngeal paracoccidioidomycosis presenting as solitary true vocal fold disease |
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