Treatment efficacy and methotrexate-related toxicity in patients with rheumatoid arthritis receiving methotrexate in combination with adalimumab

BackgroundTreatment of rheumatoid arthritis (RA) with a combination of methotrexate (MTX)+adalimumab (ADA) is more effective than ADA monotherapy. We assessed the toxicity of different doses of MTX and treatment efficacy of ADA+MTX in two trials.MethodsData originated from CONCERTO, in patients with...

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Veröffentlicht in:	Rheumatic & musculoskeletal diseases open 2017-09, Vol.3 (2), p.e000465-e000465
Hauptverfasser:	Burmester, Gerd R, Kaeley, Gurjit S, Kavanaugh, Arthur F, Gabay, Cem, MacCarter, Daryl K, Nash, Peter, Takeuchi, Tsutomu, Goss, Sandra L, Rodila, Ramona, Chen, Kun, Kupper, Hartmut, Kalabic, Jasmina
Format:	Artikel
Sprache:	eng
Schlagworte:	Drug dosages Immunotherapy Monoclonal antibodies Rheumatoid Arthritis TNF inhibitors Toxicity Tumor necrosis factor-TNF Ulcers
Online-Zugang:	Volltext
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