Exploring regulation in tissues with eQTL networks

Characterizing the collective regulatory impact of genetic variants on complex phenotypes is a major challenge in developing a genotype to phenotype map. Using expression quantitative trait locus (eQTL) analyses, we constructed bipartite networks in which edges represent significant associations bet...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2017-09, Vol.114 (37), p.E7841-E7850
Hauptverfasser:	Fagny, Maud, Paulson, Joseph N., Kuijjer, Marieke L., Sonawane, Abhijeet R., Chen, Cho-Yi, Lopes-Ramos, Camila M., Glass, Kimberly, Quackenbush, John, Platig, John
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological activity Biological Sciences Chromatin Coalescing Communities Gene expression Genotype & phenotype Life Sciences Networks PNAS Plus Quantitative trait loci Structure-function relationships Studies Tissues
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!