Cutaneous Burn Injury Promotes Shifts in the Bacterial Microbiome in Autologous Donor Skin: Implications for Skin Grafting Outcomes

INTRODUCTION:The cutaneous microbiome maintains skin barrier function, regulates inflammation, and stimulates wound-healing responses. Burn injury promotes an excessive activation of the cutaneous and systemic immune response directed against commensal and invading pathogens. Skin grafting is the pr...

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Veröffentlicht in:	Shock (Augusta, Ga.) Ga.), 2017-10, Vol.48 (4), p.441-448
Hauptverfasser:	Plichta, Jennifer K, Gao, Xiang, Lin, Huaiying, Dong, Qunfeng, Toh, Evelyn, Nelson, David E, Gamelli, Richard L, Grice, Elizabeth A, Radek, Katherine A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Autografts Bacterial Infections - etiology Bacterial Infections - microbiology Bacterial Infections - mortality Bacterial Infections - therapy Burns - microbiology Burns - mortality Burns - surgery Female Gastrointestinal Microbiome Graft Survival Humans Male Middle Aged Sepsis - etiology Sepsis - microbiology Sepsis - mortality Sepsis - therapy Skin Transplantation Wound Infection - microbiology Wound Infection - mortality Wound Infection - therapy
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