Translational repression of the Drosophila nanos mRNA involves the RNA helicase Belle and RNA coating by Me31B and Trailer hitch

Translational repression of maternal mRNAs is an essential regulatory mechanism during early embryonic development. Repression of the mRNA, required for the formation of the anterior-posterior body axis, depends on the protein Smaug binding to two Smaug recognition elements (SREs) in the 3' UTR...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	RNA (Cambridge) 2017-10, Vol.23 (10), p.1552-1568
Hauptverfasser:	Götze, Michael, Dufourt, Jérémy, Ihling, Christian, Rammelt, Christiane, Pierson, Stephanie, Sambrani, Nagraj, Temme, Claudia, Sinz, Andrea, Simonelig, Martine, Wahle, Elmar
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated regions Adenosine triphosphatase Animals DEAD-box RNA Helicases - genetics DEAD-box RNA Helicases - metabolism DNA helicase Drosophila Drosophila melanogaster - embryology Drosophila melanogaster - genetics Drosophila Proteins - genetics Drosophila Proteins - metabolism Embryo, Nonmammalian Embryogenesis Gene Expression Regulation Genetics Initiation factor eIF-4E Insects Life Sciences mRNA Multiprotein Complexes - genetics Multiprotein Complexes - metabolism Protein Biosynthesis Repressor Proteins - genetics Repressor Proteins - metabolism Ribonucleoproteins - genetics Ribonucleoproteins - metabolism RNA helicase RNA Helicases - genetics RNA Helicases - metabolism RNA, Messenger - chemistry RNA, Messenger - genetics RNA, Messenger - metabolism RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!