Automating cell detection and classification in human brain fluorescent microscopy images using dictionary learning and sparse coding

•Our method detects and classifies cells in human brain fluorescence microscopy.•Dictionary learning and sparse coding learn to better represent cells in our images.•Segmented cells are automatically classified to speed up the cell counting process.•Our method outperforms several open-access methods...

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Veröffentlicht in:Journal of neuroscience methods 2017-04, Vol.282 (C), p.20-33
Hauptverfasser: Alegro, Maryana, Theofilas, Panagiotis, Nguy, Austin, Castruita, Patricia A., Seeley, William, Heinsen, Helmut, Ushizima, Daniela M., Grinberg, Lea T.
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Sprache:eng
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