Epicutaneous allergen application preferentially boosts specific T cell responses in sensitized patients

The effects of epicutaneous allergen administration on systemic immune responses in allergic and non-allergic individuals has not been investigated with defined allergen molecules. We studied the effects of epicutaneous administration of rBet v 1 and rBet v 1 fragments on systemic immune responses i...

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Veröffentlicht in:	Scientific reports 2017-09, Vol.7 (1), p.11657-11, Article 11657
Hauptverfasser:	Campana, Raffaela, Moritz, Katharina, Neubauer, Angela, Huber, Hans, Henning, Rainer, Brodie, Tess M., Kaider, Alexandra, Sallusto, Federica, Wöhrl, Stefan, Valenta, Rudolf
Format:	Artikel
Sprache:	eng
Schlagworte:	631/250/2152/1566/20 692/699/249/2510/9 82/1 Administration, Cutaneous Allergens Allergens - administration & dosage Allergens - immunology Allergies Atopic dermatitis Bet v 1 antigen Cell proliferation Cytokines - metabolism Dermatitis Desensitization, Immunologic Humanities and Social Sciences Humans Hypersensitivity - immunology Hypersensitivity - therapy Immune response Immunity, Cellular Immunization Immunization, Secondary Immunoglobulin E Immunoglobulin E - immunology Immunoglobulin G Immunoglobulin G - immunology Leukocytes, Mononuclear - immunology Leukocytes, Mononuclear - metabolism Lymphocytes Lymphocytes T multidisciplinary Pollen Rhinoconjunctivitis Science Science (multidisciplinary) T cell receptors T-Lymphocytes - immunology T-Lymphocytes - metabolism
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