TNFα deficiency results in increased IL-1β in an early onset of spontaneous murine colitis

Inflammatory bowel disease (Crohn’s disease (CD) and ulcerative colitis (UC)) is a multifactorial disease resulting from immune dysregulation in the gut. The underlying colitis is characterized by high levels of inflammatory cytokines, including TNF α . Biological intervention for IBD patients using...

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Veröffentlicht in:Cell death & disease 2017-08, Vol.8 (8), p.e2993-e2993
Hauptverfasser: De Santis, S, Kunde, D, Galleggiante, V, Liso, M, Scandiffio, L, Serino, G, Pinto, A, Campiglia, P, Sorrentino, R, Cavalcanti, E, Santino, A, Caruso, M L, Eri, R, Chieppa, M
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Sprache:eng
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