Successful Treatment of TAFRO Syndrome with Tocilizumab, Prednisone, and Cyclophosphamide

TAFRO syndrome is a rare systemic inflammatory disease characterized by thrombocytopenia, pleural effusion, fever, renal dysfunction, reticulin fibrosis of the bone marrow, and organomegaly. The clinical course varies significantly among patients. However, the prognosis is usually dismal in patients...

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Veröffentlicht in:	Internal Medicine 2017/08/15, Vol.56(16), pp.2205-2211
Hauptverfasser:	Kikuchi, Taku, Shimizu, Takayuki, Toyama, Takaaki, Abe, Ryohei, Okamoto, Shinichiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antibodies, Monoclonal, Humanized - therapeutic use Bone marrow Bone Marrow - pathology Case Report Cyclophosphamide Cyclophosphamide - therapeutic use Drug Therapy, Combination Edema - drug therapy Fever Fever - drug therapy Fibrosis Glucocorticoids - therapeutic use Humans Internal medicine Lymphadenopathy - diagnostic imaging Lymphadenopathy - drug therapy Male Patients Pleural effusion Pleural Effusion - diagnostic imaging Pleural Effusion - drug therapy Prednisone Prednisone - therapeutic use Renal function Syndrome TAFRO syndrome Thrombocytopenia Thrombocytopenia - drug therapy tocilizumab Tomography, X-Ray Computed
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