Nrf2 as a target for prevention of age‐related and diabetic cataracts by against oxidative stress

Summary Cataract is one of the most important causes of blindness worldwide, with age‐related cataract being the most common one. Agents preventing cataract formation are urgently required. Substantial evidences point out aggravated oxidative stress as a vital factor for cataract formation. Nuclear...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Aging cell 2017-10, Vol.16 (5), p.934-942
Hauptverfasser:	Liu, Xiu‐Fen, Hao, Ji‐Long, Xie, Tian, Malik, Tayyab Hamid, Lu, Cheng‐Bo, Liu, Cong, Shu, Chang, Lu, Cheng‐Wei, Zhou, Dan‐Dan
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Aging - genetics Aging - metabolism antioxidant response element Antioxidants - therapeutic use Benzofurans - therapeutic use Blindness Blindness - genetics Blindness - metabolism Blindness - pathology Blindness - prevention & control Cataract Cataract - genetics Cataract - metabolism Cataract - pathology Cataract - prevention & control Cataracts Diabetes mellitus Flavonoids - therapeutic use Gene Expression Regulation, Developmental Health aspects Homology Humans Keap1 Kelch-Like ECH-Associated Protein 1 - genetics Kelch-Like ECH-Associated Protein 1 - metabolism Lens, Crystalline lenses NF-E2-Related Factor 2 - agonists NF-E2-Related Factor 2 - genetics NF-E2-Related Factor 2 - metabolism Nrf2 Oxidative stress Oxidative Stress - drug effects Quercetin - analogs & derivatives Quercetin - therapeutic use Review Reviews Signal Transduction Transcription, Genetic
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!