HSP90 inhibitor 17-DMAG exerts anticancer effects against gastric cancer cells principally by altering oxidant-antioxidant balance

Heat shock protein 90 (HSP90) stabilizes numerous oncoproteins and, therefore, its inhibition has emerged as a promising antineoplastic strategy for diverse malignancies. In this study, we determined the therapeutic effects and mechanisms of action of a specific HSP90 inhibitor, 17-dimethylamino-eth...

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Veröffentlicht in:Oncotarget 2017-08, Vol.8 (34), p.56473-56489
Hauptverfasser: Kim, Jeong Goo, Lee, Sang Chul, Kim, Ok-Hee, Kim, Kee-Hwan, Song, Kyo Young, Lee, Sang Kuon, Choi, Byung Jo, Jeong, Wonjun, Kim, Say-June
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Sprache:eng
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