Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade

Prostate cancer (PCa) is the most common malignancy among Western men and the second leading-cause of cancer related deaths. For men who develop metastatic castration resistant PCa (mCRPC), survival is limited, making the identification of novel therapies for mCRPC critical. We have found that defic...

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Veröffentlicht in:Oncotarget 2017-08, Vol.8 (34), p.56051-56065
Hauptverfasser: Flaig, Thomas W, Salzmann-Sullivan, Maren, Su, Lih-Jen, Zhang, Zhiyong, Joshi, Molishree, Gijón, Miguel A, Kim, Jihye, Arcaroli, John J, Van Bokhoven, Adrie, Lucia, M Scott, La Rosa, Francisco G, Schlaepfer, Isabel R
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Sprache:eng
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