The exocyst is required for photoreceptor ciliogenesis and retinal development

We previously have shown that the highly conserved eight-protein exocyst trafficking complex is required for ciliogenesis in kidney tubule cells. We hypothesized here that ciliogenic programs are conserved across organs and species. To determine whether renal primary ciliogenic programs are conserve...

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Veröffentlicht in:	The Journal of biological chemistry 2017-09, Vol.292 (36), p.14814-14826
Hauptverfasser:	Lobo, Glenn P., Fulmer, Diana, Guo, Lilong, Zuo, Xiaofeng, Dang, Yujing, Kim, Seok-Hyung, Su, Yanhui, George, Kola, Obert, Elisabeth, Fogelgren, Ben, Nihalani, Deepak, Norris, Russell A., Rohrer, Bärbel, Lipschutz, Joshua H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cilia - metabolism Developmental Biology exocyst Exocytosis eye Mice Mice, Inbred C57BL Mutation photoreceptor Photoreceptor Cells, Vertebrate - metabolism Photoreceptor Cells, Vertebrate - pathology primary cilium Retina - metabolism Retina - pathology retinal degeneration Vesicular Transport Proteins - deficiency Vesicular Transport Proteins - metabolism Zebrafish
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