Antagonistic effects of endostatin-vascular endothelial growth inhibitor chimeric recombinant adenovirus on homocysteine-induced vascular endothelial cells injury in vitro and in vivo

The study is inclined to investigate the antagonistic effects of endostatin-vascular endothelial growth inhibitor chimeric recombinant adenovirus (Ad-hENDO-VEGI) on homocysteine (Hcy)-induced vascular endothelial cells (VECs) injury in vitro and in vivo. Human VECs cell line ECV304 was selected and...

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Veröffentlicht in:	Medicine (Baltimore) 2016-11, Vol.95 (44), p.e5197-e5197
Hauptverfasser:	Cui, Zhen-Tian, Liu, Jian-Ping, Yao, Jian-Min
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae Animals Cells, Cultured Chimera Clinical Trial/Experimental Study Endostatins Endothelial Cells - drug effects Endothelial Cells - virology Homocysteine - pharmacology Homocysteine - physiology Humans Male Rats Rats, Wistar Vascular Endothelial Growth Factors - antagonists & inhibitors
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