Age‐dependent alterations to paraventricular nucleus insulin‐like growth factor 1 receptor as a possible link between sympathoexcitation and inflammation

Modifications to neural circuits of the paraventricular hypothalamic nucleus (PVN) have been implicated in sympathoexcitation and systemic cardiovascular dysfunction. However, to date, the role of insulin‐like growth factor 1 receptor (IGF‐1R) expression on PVN pathophysiology is unknown. Using conf...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neurochemistry 2016-12, Vol.139 (5), p.706-721
Hauptverfasser:	Ogundele, Olalekan M., Lee, Charles C., Francis, Joseph
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Age Factors angiotensin II Angiotensin II - toxicity Animals Astrocytes - drug effects Astrocytes - metabolism EPSCs IGF‐1/IGF‐1R Inflammation Inflammation - chemically induced Inflammation - metabolism Inflammation Mediators - metabolism Insulin-like growth factors Male Microglia - drug effects Microglia - metabolism Neurochemistry Organ Culture Techniques Paraventricular Hypothalamic Nucleus - drug effects Paraventricular Hypothalamic Nucleus - metabolism PVN Rats Rats, Inbred SHR Rats, Inbred WKY Receptor, IGF Type 1 - biosynthesis Rodents SHR sympathoexcitation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!