An enhancer element 6 kb upstream of the mouse HNF4α1 promoter is activated by glucocorticoids and liver-enriched transcription factors
We have characterized a 700 bp enhancer element around –6 kb relative to the HNF4α1 transcription start. This element increases activity and confers glucocorticoid induction to a heterologous as well as the homologous promoters in differentiated hepatoma cells and is transactivated by HNF4α1, HNF4α7...
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Veröffentlicht in: | Nucleic acids research 2001-09, Vol.29 (17), p.3495-3505 |
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Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
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