An enhancer element 6 kb upstream of the mouse HNF4α1 promoter is activated by glucocorticoids and liver-enriched transcription factors

We have characterized a 700 bp enhancer element around –6 kb relative to the HNF4α1 transcription start. This element increases activity and confers glucocorticoid induction to a heterologous as well as the homologous promoters in differentiated hepatoma cells and is transactivated by HNF4α1, HNF4α7...

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Veröffentlicht in:Nucleic acids research 2001-09, Vol.29 (17), p.3495-3505
Hauptverfasser: Bailly, Alain, Torres-Padilla, Maria Elena, Tinel, Antoine P., Weiss, Mary C.
Format: Artikel
Sprache:eng
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