Diagnostic accuracy of standardised qualitative sensory test in the detection of lumbar lateral stenosis involving the L5 nerve root
Misdiagnosis of symptomatic lumbar lateral stenosis (LS) may result in an unfavourable prognosis after surgical treatment. This study investigated the diagnostic accuracy of a standardised qualitative sensory test (SQST) in the detection of symptomatic LS in patients who had degenerative spinal diso...
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description | Misdiagnosis of symptomatic lumbar lateral stenosis (LS) may result in an unfavourable prognosis after surgical treatment. This study investigated the diagnostic accuracy of a standardised qualitative sensory test (SQST) in the detection of symptomatic LS in patients who had degenerative spinal disorders involving the L5 spinal nerve. We prospectively identified 75 patients, of which 60 met the inclusion criteria. Lateral recess stenosis at the L5 level or foraminal stenosis at the L5/S1 level on MRI was identified and graded by a neurosurgeon blinded to any clinical information. The reference criteria for the diagnosis of symptomatic LS were grade III LS on MRI and relevant clinical symptoms. Cutaneous sensory functions of the L5 dermatome on the symptomatic side were evaluated using the SQST. Each item of the SQST showed a satisfactory performance in the diagnosis of LS (sensitivity = 0.455–0.727, specificity = 0.868–1.0). A stepwise selection model identified low-strength von-Frey, high-strength von-Frey, and vibration as the most accurate predictors of symptomatic LS with an area under the receiver operating characteristic curve of 0.9563 (95% confidence interval = 0.9003–1.0). In combination with MRI, the SQST is a promising diagnostic tool for detecting symptomatic LS involving L5 nerve roots. |
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This study investigated the diagnostic accuracy of a standardised qualitative sensory test (SQST) in the detection of symptomatic LS in patients who had degenerative spinal disorders involving the L5 spinal nerve. We prospectively identified 75 patients, of which 60 met the inclusion criteria. Lateral recess stenosis at the L5 level or foraminal stenosis at the L5/S1 level on MRI was identified and graded by a neurosurgeon blinded to any clinical information. The reference criteria for the diagnosis of symptomatic LS were grade III LS on MRI and relevant clinical symptoms. Cutaneous sensory functions of the L5 dermatome on the symptomatic side were evaluated using the SQST. Each item of the SQST showed a satisfactory performance in the diagnosis of LS (sensitivity = 0.455–0.727, specificity = 0.868–1.0). A stepwise selection model identified low-strength von-Frey, high-strength von-Frey, and vibration as the most accurate predictors of symptomatic LS with an area under the receiver operating characteristic curve of 0.9563 (95% confidence interval = 0.9003–1.0). In combination with MRI, the SQST is a promising diagnostic tool for detecting symptomatic LS involving L5 nerve roots.</description><identifier>ISSN: 2045-2322</identifier><identifier>EISSN: 2045-2322</identifier><identifier>DOI: 10.1038/s41598-017-10641-2</identifier><identifier>PMID: 28878316</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>692/1807/410/2610 ; 692/699/375/1692 ; Accuracy ; Adult ; Aged ; Back pain ; Back Pain - diagnosis ; Back Pain - etiology ; Back surgery ; Cold ; Constriction, Pathologic - diagnosis ; Cross-Sectional Studies ; Female ; Hospitals ; Humanities and Social Sciences ; Humans ; Lumbar Vertebrae - pathology ; Lumbosacral Plexus - physiopathology ; Lumbosacral Region - pathology ; Magnetic Resonance Imaging ; Male ; Middle Aged ; multidisciplinary ; Neurosurgery ; Patients ; Reproducibility of Results ; ROC Curve ; Science ; Science (multidisciplinary) ; Sensitivity and Specificity ; Severity of Illness Index ; Somatosensory Disorders - diagnosis ; Somatosensory Disorders - etiology ; Stenosis ; Symptom Assessment</subject><ispartof>Scientific reports, 2017-09, Vol.7 (1), p.10598-9, Article 10598</ispartof><rights>The Author(s) 2017</rights><rights>2017. 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This study investigated the diagnostic accuracy of a standardised qualitative sensory test (SQST) in the detection of symptomatic LS in patients who had degenerative spinal disorders involving the L5 spinal nerve. We prospectively identified 75 patients, of which 60 met the inclusion criteria. Lateral recess stenosis at the L5 level or foraminal stenosis at the L5/S1 level on MRI was identified and graded by a neurosurgeon blinded to any clinical information. The reference criteria for the diagnosis of symptomatic LS were grade III LS on MRI and relevant clinical symptoms. Cutaneous sensory functions of the L5 dermatome on the symptomatic side were evaluated using the SQST. Each item of the SQST showed a satisfactory performance in the diagnosis of LS (sensitivity = 0.455–0.727, specificity = 0.868–1.0). A stepwise selection model identified low-strength von-Frey, high-strength von-Frey, and vibration as the most accurate predictors of symptomatic LS with an area under the receiver operating characteristic curve of 0.9563 (95% confidence interval = 0.9003–1.0). In combination with MRI, the SQST is a promising diagnostic tool for detecting symptomatic LS involving L5 nerve roots.</description><subject>692/1807/410/2610</subject><subject>692/699/375/1692</subject><subject>Accuracy</subject><subject>Adult</subject><subject>Aged</subject><subject>Back pain</subject><subject>Back Pain - diagnosis</subject><subject>Back Pain - etiology</subject><subject>Back surgery</subject><subject>Cold</subject><subject>Constriction, Pathologic - diagnosis</subject><subject>Cross-Sectional Studies</subject><subject>Female</subject><subject>Hospitals</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>Lumbar Vertebrae - pathology</subject><subject>Lumbosacral Plexus - physiopathology</subject><subject>Lumbosacral Region - pathology</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Middle Aged</subject><subject>multidisciplinary</subject><subject>Neurosurgery</subject><subject>Patients</subject><subject>Reproducibility of Results</subject><subject>ROC Curve</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Sensitivity and Specificity</subject><subject>Severity of Illness Index</subject><subject>Somatosensory Disorders - 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diagnosis</topic><topic>Back Pain - etiology</topic><topic>Back surgery</topic><topic>Cold</topic><topic>Constriction, Pathologic - diagnosis</topic><topic>Cross-Sectional Studies</topic><topic>Female</topic><topic>Hospitals</topic><topic>Humanities and Social Sciences</topic><topic>Humans</topic><topic>Lumbar Vertebrae - pathology</topic><topic>Lumbosacral Plexus - physiopathology</topic><topic>Lumbosacral Region - pathology</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Middle Aged</topic><topic>multidisciplinary</topic><topic>Neurosurgery</topic><topic>Patients</topic><topic>Reproducibility of Results</topic><topic>ROC Curve</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Sensitivity and Specificity</topic><topic>Severity of Illness Index</topic><topic>Somatosensory Disorders - diagnosis</topic><topic>Somatosensory Disorders - etiology</topic><topic>Stenosis</topic><topic>Symptom Assessment</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lin, Jiann-Her</creatorcontrib><creatorcontrib>Hsieh, Yi-Chen</creatorcontrib><creatorcontrib>Chen, Yi-Chen</creatorcontrib><creatorcontrib>Wang, Yun</creatorcontrib><creatorcontrib>Chen, Chih-Cheng</creatorcontrib><creatorcontrib>Chiang, Yung-Hsiao</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Scientific reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lin, Jiann-Her</au><au>Hsieh, Yi-Chen</au><au>Chen, Yi-Chen</au><au>Wang, Yun</au><au>Chen, Chih-Cheng</au><au>Chiang, Yung-Hsiao</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diagnostic accuracy of standardised qualitative sensory test in the detection of lumbar lateral stenosis involving the L5 nerve root</atitle><jtitle>Scientific reports</jtitle><stitle>Sci Rep</stitle><addtitle>Sci Rep</addtitle><date>2017-09-06</date><risdate>2017</risdate><volume>7</volume><issue>1</issue><spage>10598</spage><epage>9</epage><pages>10598-9</pages><artnum>10598</artnum><issn>2045-2322</issn><eissn>2045-2322</eissn><abstract>Misdiagnosis of symptomatic lumbar lateral stenosis (LS) may result in an unfavourable prognosis after surgical treatment. This study investigated the diagnostic accuracy of a standardised qualitative sensory test (SQST) in the detection of symptomatic LS in patients who had degenerative spinal disorders involving the L5 spinal nerve. We prospectively identified 75 patients, of which 60 met the inclusion criteria. Lateral recess stenosis at the L5 level or foraminal stenosis at the L5/S1 level on MRI was identified and graded by a neurosurgeon blinded to any clinical information. The reference criteria for the diagnosis of symptomatic LS were grade III LS on MRI and relevant clinical symptoms. Cutaneous sensory functions of the L5 dermatome on the symptomatic side were evaluated using the SQST. Each item of the SQST showed a satisfactory performance in the diagnosis of LS (sensitivity = 0.455–0.727, specificity = 0.868–1.0). A stepwise selection model identified low-strength von-Frey, high-strength von-Frey, and vibration as the most accurate predictors of symptomatic LS with an area under the receiver operating characteristic curve of 0.9563 (95% confidence interval = 0.9003–1.0). In combination with MRI, the SQST is a promising diagnostic tool for detecting symptomatic LS involving L5 nerve roots.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>28878316</pmid><doi>10.1038/s41598-017-10641-2</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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subjects | 692/1807/410/2610 692/699/375/1692 Accuracy Adult Aged Back pain Back Pain - diagnosis Back Pain - etiology Back surgery Cold Constriction, Pathologic - diagnosis Cross-Sectional Studies Female Hospitals Humanities and Social Sciences Humans Lumbar Vertebrae - pathology Lumbosacral Plexus - physiopathology Lumbosacral Region - pathology Magnetic Resonance Imaging Male Middle Aged multidisciplinary Neurosurgery Patients Reproducibility of Results ROC Curve Science Science (multidisciplinary) Sensitivity and Specificity Severity of Illness Index Somatosensory Disorders - diagnosis Somatosensory Disorders - etiology Stenosis Symptom Assessment |
title | Diagnostic accuracy of standardised qualitative sensory test in the detection of lumbar lateral stenosis involving the L5 nerve root |
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