Nanotechnology Approaches for the Delivery of Exogenous siRNA for HIV Therapy

RNA interference (RNAi) is triggered by oligonucleotides that are about 21–23 nucleotides long and are capable of inducing the destruction of complementary mRNA. The RNAi technique has been successfully utilized to target HIV replication; however, the main limitation to the successful utilization of...

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Veröffentlicht in:	Molecular pharmaceutics 2015-12, Vol.12 (12), p.4175-4187
Hauptverfasser:	Adesina, Simeon K, Akala, Emmanuel O
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-HIV Agents - administration & dosage Drug Delivery Systems - methods HIV Infections - genetics HIV Infections - therapy Humans Nanoparticles - administration & dosage Nanotechnology - methods RNA Interference - physiology RNA, Small Interfering - genetics
Online-Zugang:	Volltext
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