Cerebral hyperperfusion on arterial spin labeling MRI after reperfusion therapy is related to hemorrhagic transformation
Early detection of hemorrhagic transformation after reperfusion therapy is crucial in acute stroke treatment. Here, we evaluated the relationship between hemorrhagic transformation and post-reperfusion hyperperfusion using pulsed arterial spin labeling (ASL) perfusion MRI and 123I-iodoamphetamine si...
Gespeichert in:
| Veröffentlicht in: | Journal of cerebral blood flow and metabolism 2017-09, Vol.37 (9), p.3087-3090 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 3090 |
|---|---|
| container_issue | 9 |
| container_start_page | 3087 |
| container_title | Journal of cerebral blood flow and metabolism |
| container_volume | 37 |
| creator | Okazaki, Shuhei Yamagami, Hiroshi Yoshimoto, Takeshi Morita, Yoshiaki Yamamoto, Haruko Toyoda, Kazunori Ihara, Masafumi |
| description | Early detection of hemorrhagic transformation after reperfusion therapy is crucial in acute stroke treatment. Here, we evaluated the relationship between hemorrhagic transformation and post-reperfusion hyperperfusion using pulsed arterial spin labeling (ASL) perfusion MRI and 123I-iodoamphetamine single-photon emission-computed tomography. Patients who developed hemorrhagic transformation showed significantly higher cerebral blood flow in the affected lesion after thrombolysis and/or endovascular intervention. Focal hyperperfusion (ipsilateral to contralateral ratio >1.5) was associated with hemorrhagic transformation after reperfusion (odds ratio, 9.3; 95% confidence interval, 1.4–64.0). Our findings suggest that post-reperfusion hyperperfusion on ASL could represent a reliable marker of hemorrhagic transformation. |
| doi_str_mv | 10.1177/0271678X17718099 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5584703</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_0271678X17718099</sage_id><sourcerecordid>1915343946</sourcerecordid><originalsourceid>FETCH-LOGICAL-c547t-b4a6d58c490e61a71b9b9bbdc3e98190f0e056ec32d66750088ef738b0f0321a3</originalsourceid><addsrcrecordid>eNp1UUtr3DAQFqGl2Sa951R07MWNtLJel0JZ-gikBEoCuQnZHq8VbMsd2aX776Nl82gLQQMa9D000kfIGWcfOdf6nK01V9rc5p4bZu0RWXEpbaEZV6_Iag8Xe_yYvE3pjjFmhJRvyPHaKCW5MivyZwMIFfqedrsJMFe7pBBHmsvjDBgylKYw0t5X0IdxS3_8vKC-zRBFeObPHaCfdjSkfNz7GRo6R9rBEBE7vw01ndGPqY04-DkLTsnr1vcJ3j3sJ-Tm65frzffi8urbxebzZVHLUs9FVXrVSFOXloHiXvPK5lU1tQBruGUtAyYV1GLdKKVlfqGBVgtTZUSsuRcn5NPBd1qqAZoaxjxH7yYMg8ediz64f5ExdG4bfzspTamZyAYfHgww_logzW4IqYa-9yPEJTluuRSlsKXKVHag1hhTQmifruHM7QNz_weWJe__Hu9J8JhQJhQHQvJbcHdxwTF_18uG91-MofI</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1915343946</pqid></control><display><type>article</type><title>Cerebral hyperperfusion on arterial spin labeling MRI after reperfusion therapy is related to hemorrhagic transformation</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>SAGE Complete A-Z List</source><source>PubMed Central</source><creator>Okazaki, Shuhei ; Yamagami, Hiroshi ; Yoshimoto, Takeshi ; Morita, Yoshiaki ; Yamamoto, Haruko ; Toyoda, Kazunori ; Ihara, Masafumi</creator><creatorcontrib>Okazaki, Shuhei ; Yamagami, Hiroshi ; Yoshimoto, Takeshi ; Morita, Yoshiaki ; Yamamoto, Haruko ; Toyoda, Kazunori ; Ihara, Masafumi</creatorcontrib><description>Early detection of hemorrhagic transformation after reperfusion therapy is crucial in acute stroke treatment. Here, we evaluated the relationship between hemorrhagic transformation and post-reperfusion hyperperfusion using pulsed arterial spin labeling (ASL) perfusion MRI and 123I-iodoamphetamine single-photon emission-computed tomography. Patients who developed hemorrhagic transformation showed significantly higher cerebral blood flow in the affected lesion after thrombolysis and/or endovascular intervention. Focal hyperperfusion (ipsilateral to contralateral ratio >1.5) was associated with hemorrhagic transformation after reperfusion (odds ratio, 9.3; 95% confidence interval, 1.4–64.0). Our findings suggest that post-reperfusion hyperperfusion on ASL could represent a reliable marker of hemorrhagic transformation.</description><identifier>ISSN: 0271-678X</identifier><identifier>EISSN: 1559-7016</identifier><identifier>DOI: 10.1177/0271678X17718099</identifier><identifier>PMID: 28665168</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Brief Communications ; Cerebrovascular Circulation - physiology ; Diffusion Magnetic Resonance Imaging ; Endovascular Procedures - adverse effects ; Humans ; Image Interpretation, Computer-Assisted ; Infarction, Middle Cerebral Artery - diagnostic imaging ; Infarction, Middle Cerebral Artery - physiopathology ; Infarction, Middle Cerebral Artery - therapy ; Intracranial Hemorrhages - diagnostic imaging ; Intracranial Hemorrhages - etiology ; Intracranial Hemorrhages - physiopathology ; Linear Models ; Reperfusion - adverse effects ; Reperfusion Injury - diagnostic imaging ; Reperfusion Injury - etiology ; Reperfusion Injury - physiopathology ; Spin Labels ; Thrombolytic Therapy - adverse effects ; Tomography, Emission-Computed, Single-Photon</subject><ispartof>Journal of cerebral blood flow and metabolism, 2017-09, Vol.37 (9), p.3087-3090</ispartof><rights>The Author(s) 2017</rights><rights>The Author(s) 2017 2017 International Society for Cerebral Blood Flow and Metabolism</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c547t-b4a6d58c490e61a71b9b9bbdc3e98190f0e056ec32d66750088ef738b0f0321a3</citedby><cites>FETCH-LOGICAL-c547t-b4a6d58c490e61a71b9b9bbdc3e98190f0e056ec32d66750088ef738b0f0321a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584703/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584703/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,21799,27903,27904,43600,43601,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28665168$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Okazaki, Shuhei</creatorcontrib><creatorcontrib>Yamagami, Hiroshi</creatorcontrib><creatorcontrib>Yoshimoto, Takeshi</creatorcontrib><creatorcontrib>Morita, Yoshiaki</creatorcontrib><creatorcontrib>Yamamoto, Haruko</creatorcontrib><creatorcontrib>Toyoda, Kazunori</creatorcontrib><creatorcontrib>Ihara, Masafumi</creatorcontrib><title>Cerebral hyperperfusion on arterial spin labeling MRI after reperfusion therapy is related to hemorrhagic transformation</title><title>Journal of cerebral blood flow and metabolism</title><addtitle>J Cereb Blood Flow Metab</addtitle><description>Early detection of hemorrhagic transformation after reperfusion therapy is crucial in acute stroke treatment. Here, we evaluated the relationship between hemorrhagic transformation and post-reperfusion hyperperfusion using pulsed arterial spin labeling (ASL) perfusion MRI and 123I-iodoamphetamine single-photon emission-computed tomography. Patients who developed hemorrhagic transformation showed significantly higher cerebral blood flow in the affected lesion after thrombolysis and/or endovascular intervention. Focal hyperperfusion (ipsilateral to contralateral ratio >1.5) was associated with hemorrhagic transformation after reperfusion (odds ratio, 9.3; 95% confidence interval, 1.4–64.0). Our findings suggest that post-reperfusion hyperperfusion on ASL could represent a reliable marker of hemorrhagic transformation.</description><subject>Brief Communications</subject><subject>Cerebrovascular Circulation - physiology</subject><subject>Diffusion Magnetic Resonance Imaging</subject><subject>Endovascular Procedures - adverse effects</subject><subject>Humans</subject><subject>Image Interpretation, Computer-Assisted</subject><subject>Infarction, Middle Cerebral Artery - diagnostic imaging</subject><subject>Infarction, Middle Cerebral Artery - physiopathology</subject><subject>Infarction, Middle Cerebral Artery - therapy</subject><subject>Intracranial Hemorrhages - diagnostic imaging</subject><subject>Intracranial Hemorrhages - etiology</subject><subject>Intracranial Hemorrhages - physiopathology</subject><subject>Linear Models</subject><subject>Reperfusion - adverse effects</subject><subject>Reperfusion Injury - diagnostic imaging</subject><subject>Reperfusion Injury - etiology</subject><subject>Reperfusion Injury - physiopathology</subject><subject>Spin Labels</subject><subject>Thrombolytic Therapy - adverse effects</subject><subject>Tomography, Emission-Computed, Single-Photon</subject><issn>0271-678X</issn><issn>1559-7016</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1UUtr3DAQFqGl2Sa951R07MWNtLJel0JZ-gikBEoCuQnZHq8VbMsd2aX776Nl82gLQQMa9D000kfIGWcfOdf6nK01V9rc5p4bZu0RWXEpbaEZV6_Iag8Xe_yYvE3pjjFmhJRvyPHaKCW5MivyZwMIFfqedrsJMFe7pBBHmsvjDBgylKYw0t5X0IdxS3_8vKC-zRBFeObPHaCfdjSkfNz7GRo6R9rBEBE7vw01ndGPqY04-DkLTsnr1vcJ3j3sJ-Tm65frzffi8urbxebzZVHLUs9FVXrVSFOXloHiXvPK5lU1tQBruGUtAyYV1GLdKKVlfqGBVgtTZUSsuRcn5NPBd1qqAZoaxjxH7yYMg8ediz64f5ExdG4bfzspTamZyAYfHgww_logzW4IqYa-9yPEJTluuRSlsKXKVHag1hhTQmifruHM7QNz_weWJe__Hu9J8JhQJhQHQvJbcHdxwTF_18uG91-MofI</recordid><startdate>20170901</startdate><enddate>20170901</enddate><creator>Okazaki, Shuhei</creator><creator>Yamagami, Hiroshi</creator><creator>Yoshimoto, Takeshi</creator><creator>Morita, Yoshiaki</creator><creator>Yamamoto, Haruko</creator><creator>Toyoda, Kazunori</creator><creator>Ihara, Masafumi</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20170901</creationdate><title>Cerebral hyperperfusion on arterial spin labeling MRI after reperfusion therapy is related to hemorrhagic transformation</title><author>Okazaki, Shuhei ; Yamagami, Hiroshi ; Yoshimoto, Takeshi ; Morita, Yoshiaki ; Yamamoto, Haruko ; Toyoda, Kazunori ; Ihara, Masafumi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c547t-b4a6d58c490e61a71b9b9bbdc3e98190f0e056ec32d66750088ef738b0f0321a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Brief Communications</topic><topic>Cerebrovascular Circulation - physiology</topic><topic>Diffusion Magnetic Resonance Imaging</topic><topic>Endovascular Procedures - adverse effects</topic><topic>Humans</topic><topic>Image Interpretation, Computer-Assisted</topic><topic>Infarction, Middle Cerebral Artery - diagnostic imaging</topic><topic>Infarction, Middle Cerebral Artery - physiopathology</topic><topic>Infarction, Middle Cerebral Artery - therapy</topic><topic>Intracranial Hemorrhages - diagnostic imaging</topic><topic>Intracranial Hemorrhages - etiology</topic><topic>Intracranial Hemorrhages - physiopathology</topic><topic>Linear Models</topic><topic>Reperfusion - adverse effects</topic><topic>Reperfusion Injury - diagnostic imaging</topic><topic>Reperfusion Injury - etiology</topic><topic>Reperfusion Injury - physiopathology</topic><topic>Spin Labels</topic><topic>Thrombolytic Therapy - adverse effects</topic><topic>Tomography, Emission-Computed, Single-Photon</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Okazaki, Shuhei</creatorcontrib><creatorcontrib>Yamagami, Hiroshi</creatorcontrib><creatorcontrib>Yoshimoto, Takeshi</creatorcontrib><creatorcontrib>Morita, Yoshiaki</creatorcontrib><creatorcontrib>Yamamoto, Haruko</creatorcontrib><creatorcontrib>Toyoda, Kazunori</creatorcontrib><creatorcontrib>Ihara, Masafumi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of cerebral blood flow and metabolism</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Okazaki, Shuhei</au><au>Yamagami, Hiroshi</au><au>Yoshimoto, Takeshi</au><au>Morita, Yoshiaki</au><au>Yamamoto, Haruko</au><au>Toyoda, Kazunori</au><au>Ihara, Masafumi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cerebral hyperperfusion on arterial spin labeling MRI after reperfusion therapy is related to hemorrhagic transformation</atitle><jtitle>Journal of cerebral blood flow and metabolism</jtitle><addtitle>J Cereb Blood Flow Metab</addtitle><date>2017-09-01</date><risdate>2017</risdate><volume>37</volume><issue>9</issue><spage>3087</spage><epage>3090</epage><pages>3087-3090</pages><issn>0271-678X</issn><eissn>1559-7016</eissn><abstract>Early detection of hemorrhagic transformation after reperfusion therapy is crucial in acute stroke treatment. Here, we evaluated the relationship between hemorrhagic transformation and post-reperfusion hyperperfusion using pulsed arterial spin labeling (ASL) perfusion MRI and 123I-iodoamphetamine single-photon emission-computed tomography. Patients who developed hemorrhagic transformation showed significantly higher cerebral blood flow in the affected lesion after thrombolysis and/or endovascular intervention. Focal hyperperfusion (ipsilateral to contralateral ratio >1.5) was associated with hemorrhagic transformation after reperfusion (odds ratio, 9.3; 95% confidence interval, 1.4–64.0). Our findings suggest that post-reperfusion hyperperfusion on ASL could represent a reliable marker of hemorrhagic transformation.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>28665168</pmid><doi>10.1177/0271678X17718099</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0271-678X |
| ispartof | Journal of cerebral blood flow and metabolism, 2017-09, Vol.37 (9), p.3087-3090 |
| issn | 0271-678X 1559-7016 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5584703 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; SAGE Complete A-Z List; PubMed Central |
| subjects | Brief Communications Cerebrovascular Circulation - physiology Diffusion Magnetic Resonance Imaging Endovascular Procedures - adverse effects Humans Image Interpretation, Computer-Assisted Infarction, Middle Cerebral Artery - diagnostic imaging Infarction, Middle Cerebral Artery - physiopathology Infarction, Middle Cerebral Artery - therapy Intracranial Hemorrhages - diagnostic imaging Intracranial Hemorrhages - etiology Intracranial Hemorrhages - physiopathology Linear Models Reperfusion - adverse effects Reperfusion Injury - diagnostic imaging Reperfusion Injury - etiology Reperfusion Injury - physiopathology Spin Labels Thrombolytic Therapy - adverse effects Tomography, Emission-Computed, Single-Photon |
| title | Cerebral hyperperfusion on arterial spin labeling MRI after reperfusion therapy is related to hemorrhagic transformation |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-25T07%3A27%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Cerebral%20hyperperfusion%20on%20arterial%20spin%20labeling%20MRI%20after%20reperfusion%20therapy%20is%20related%20to%20hemorrhagic%20transformation&rft.jtitle=Journal%20of%20cerebral%20blood%20flow%20and%20metabolism&rft.au=Okazaki,%20Shuhei&rft.date=2017-09-01&rft.volume=37&rft.issue=9&rft.spage=3087&rft.epage=3090&rft.pages=3087-3090&rft.issn=0271-678X&rft.eissn=1559-7016&rft_id=info:doi/10.1177/0271678X17718099&rft_dat=%3Cproquest_pubme%3E1915343946%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1915343946&rft_id=info:pmid/28665168&rft_sage_id=10.1177_0271678X17718099&rfr_iscdi=true |