Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins

Electroconvulsive seizure (ECS) is an experimental animal model of electroconvulsive therapy, the most effective treatment for severe depression. ECS induces generalized tonic-clonic seizures with low mortality and neuronal death and is a widely-used model to screen anti-epileptic drugs. Here, we de...

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Veröffentlicht in:Journal of Visualized Experiments 2017-08 (126)
Hauptverfasser: Jang, Sung-Soo, Jeong, Han Gil, Chung, Hee Jung
Format: Artikel
Sprache:eng
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