Curcumin induces G2/M cell cycle arrest and apoptosis of head and neck squamous cell carcinoma in vitro and in vivo through ATM/Chk2/p53-dependent pathway

Studies have demonstrated that curcumin (CUR) exerts its tumor suppressor function in a variety of human cancers including head and neck squamous cell carcinoma (HNSCC). However, the exact underlying molecular mechanisms remain obscure. Here, we aim to test whether CUR affects ATM/Chk2/p53 signaling...

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Veröffentlicht in:	Oncotarget 2017-08, Vol.8 (31), p.50747-50760
Hauptverfasser:	Hu, An, Huang, Jing-Juan, Zhang, Jing-Fei, Dai, Wei-Jun, Li, Rui-Lin, Lu, Zhao-Yang, Duan, Jun-Li, Li, Ji-Ping, Chen, Xiao-Ping, Fan, Jing-Ping, Xu, Wei-Hua, Zheng, Hong-Liang
Format:	Artikel
Sprache:	eng
Schlagworte:	Research Paper
Online-Zugang:	Volltext
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