p14ARF interacts with the focal adhesion kinase and protects cells from anoikis

The ARF protein functions as an important sensor of hyper-proliferative stimuli restricting cell proliferation through both p53-dependent and -independent pathways. Although to date the majority of studies on ARF have focused on its anti-proliferative role, few studies have addressed whether ARF may...

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Veröffentlicht in:	Oncogene 2017-08, Vol.36 (34), p.4913-4928
Hauptverfasser:	Vivo, M, Fontana, R, Ranieri, M, Capasso, G, Angrisano, T, Pollice, A, Calabrò, V, La Mantia, G
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/106 13/89 13/95 14/19 14/63 631/80/79/2027 631/80/82/23 82 82/29 82/80 96 96/109 Actin Anoikis Anoikis - physiology Apoptosis Apoptosis - physiology ARF protein Cancer Cell adhesion & migration Cell Adhesion - physiology Cell Biology Cell growth Cell Line, Tumor Cell proliferation Cell Proliferation - physiology Cell Survival - physiology Cytoskeleton Cytoskeleton - metabolism Cytoskeleton - physiology Death-associated protein kinase Death-Associated Protein Kinases - metabolism Focal adhesion kinase Focal Adhesion Protein-Tyrosine Kinases - metabolism Focal Adhesions - metabolism Focal Adhesions - physiology HeLa Cells Human Genetics Humans Internal Medicine Kinases MCF-7 Cells Medicine Medicine & Public Health Oncology Original original-article p53 Protein Phosphorylation - physiology Polymerization Protein kinases Proteins Signal Transduction - physiology Tumor cells Tumor proteins Tumor Suppressor Protein p14ARF - metabolism
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