Protein astrogliopathies in human neurodegenerative diseases and aging

Neurodegenerative diseases are characterized by progressive dysfunction and loss of neurons associated with depositions of pathologically altered proteins showing hierarchical involvement of brain regions. The role of astrocytes in the pathogenesis of neurodegenerative diseases is explored as contri...

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Veröffentlicht in:	Brain pathology (Zurich, Switzerland) Switzerland), 2017-09, Vol.27 (5), p.675-690
Hauptverfasser:	Kovacs, Gabor G., Lee, Virginia M., Trojanowski, John Q.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging alpha‐synuclein ARTAG astrocyte Astrocytes Astrocytes - metabolism Astrocytes - pathology A‐beta Brain Brain - metabolism Brain - pathology Brain injury Degeneration Deoxyribonucleic acid DNA DNA-binding protein Encephalopathy Frontotemporal dementia Genetic variability Head injuries Humans Mini‐symposium: Astroglia in Neurodegenerative Diseases Morphology Neurodegeneration Neurodegenerative diseases Neurodegenerative Diseases - metabolism Neurodegenerative Diseases - pathology Neurological diseases Neurons Neuroprotection PAG Pathogenesis prion Prion protein protein astrogliopathy Proteins Spreading Synuclein tau Tau protein tau Proteins - metabolism TDP‐43 β-Amyloid
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