Sleep and pulmonary outcomes for clinical trials of airway plexiform neurofibromas in NF1

OBJECTIVE:Plexiform neurofibromas (PNs) are complex, benign nerve sheath tumors that occur in approximately 25%–50% of individuals with neurofibromatosis type 1 (NF1). PNs that cause airway compromise or pulmonary dysfunction are uncommon but clinically important. Because improvement in sleep qualit...

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Veröffentlicht in:	Neurology 2016-08, Vol.87 (7_Supplement_1 Suppl 1), p.S13-S20
Hauptverfasser:	Plotkin, Scott R, Davis, Stephanie D, Robertson, Kent A, Akshintala, Srivandana, Allen, Julian, Fisher, Michael J, Blakeley, Jaishri O, Widemann, Brigitte C, Ferner, Rosalie E, Marcus, Carole L
Format:	Artikel
Sprache:	eng
Schlagworte:	Clinical Trials as Topic - methods Humans Lung - physiopathology Neurofibroma, Plexiform - physiopathology Neurofibroma, Plexiform - therapy Neurofibromatosis 1 - physiopathology Neurofibromatosis 1 - therapy Oscillometry - methods Polysomnography - methods Sleep - physiology Spirometry - methods Treatment Outcome
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