Biofilms in Endodontics-Current Status and Future Directions

Microbiota are found in highly organized and complex entities, known as biofilms, the characteristics of which are fundamentally different from microbes in planktonic suspensions. Root canal infections are biofilm mediated. The complexity and variability of the root canal system, together with the m...

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Veröffentlicht in:International journal of molecular sciences 2017-08, Vol.18 (8), p.1748
Hauptverfasser: Neelakantan, Prasanna, Romero, Monica, Vera, Jorge, Daood, Umer, Khan, Asad U, Yan, Aixin, Cheung, Gary Shun Pan
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container_issue 8
container_start_page 1748
container_title International journal of molecular sciences
container_volume 18
creator Neelakantan, Prasanna
Romero, Monica
Vera, Jorge
Daood, Umer
Khan, Asad U
Yan, Aixin
Cheung, Gary Shun Pan
description Microbiota are found in highly organized and complex entities, known as biofilms, the characteristics of which are fundamentally different from microbes in planktonic suspensions. Root canal infections are biofilm mediated. The complexity and variability of the root canal system, together with the multi-species nature of biofilms, make disinfection of this system extremely challenging. Microbial persistence appears to be the most important factor for failure of root canal treatment and this could further have an impact on pain and quality of life. Biofilm removal is accomplished by a chemo-mechanical process, using specific instruments and disinfecting chemicals in the form of irrigants and/or intracanal medicaments. Endodontic research has focused on the characterization of root canal biofilms and the clinical methods to disrupt the biofilms in addition to achieving microbial killing. In this narrative review, we discuss the role of microbial biofilms in endodontics and review the literature on the role of root canal disinfectants and disinfectant-activating methods on biofilm removal.
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; MDPI - Multidisciplinary Digital Publishing Institute; PubMed Central
subjects Animals
Biofilms
Dental Pulp Cavity - microbiology
Disinfectants
Disinfection
Disinfection & disinfectants
Endodontics
Endodontics - methods
Humans
Literature reviews
Microbiology
Microorganisms
Pain
Quality of life
Review
Root Canal Therapy - methods
Root canals
title Biofilms in Endodontics-Current Status and Future Directions
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