Transcriptomic analysis identifies a role of PI3K–Akt signalling in the responses of skeletal muscle to acute hypoxia in vivo

Key points Changes in gene expression that occur within hours of exposure to hypoxia in in vivo skeletal muscles remain unexplored. Two hours of hypoxia caused significant down‐regulation of extracellular matrix genes followed by a shift at 6 h to altered expression of genes associated with the nucl...

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