A Personalized Model of COQ2 Nephropathy Rescued by the Wild-Type COQ2 Allele or Dietary Coenzyme Q10 Supplementation

Clinical studies have identified patients with nephrotic syndrome caused by mutations in genes involved in the biosynthesis of coenzyme Q 10 (CoQ 10 ), a lipid component of the mitochondrial electron transport chain and an important antioxidant. However, the cellular mechanisms through which these m...

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Veröffentlicht in:	Journal of the American Society of Nephrology 2017-09, Vol.28 (9), p.2607-2617
Hauptverfasser:	Zhu, Jun-yi, Fu, Yulong, Richman, Adam, Zhao, Zhanzheng, Ray, Patricio E., Han, Zhe
Format:	Artikel
Sprache:	eng
Schlagworte:	Basic Research
Online-Zugang:	Volltext
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