The tumor promoter‐activated protein kinase Cs are a system for regulating filopodia

Different protein kinase C (PKC) isoforms have distinct roles in regulating cell functions. The conventional (α, β, γ) and novel (δ, ɛ, η, θ) classes are targets of phorbol ester tumor promoters, which are surrogates of endogenous second messenger, diacylglycerol. The promoter‐stimulated disappearan...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cytoskeleton (Hoboken, N.J.) N.J.), 2017-08, Vol.74 (8), p.297-314
Hauptverfasser:	Heckman, Carol A., Pandey, Pratima, Cayer, Marilyn L., Biswas, Tania, Zhang, Zhong‐Yin, Boudreau, Nancy S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism adhesion Amino Acid Sequence Animals cancer Carcinogens - toxicity Cell Line Chemotaxis contact inhibition Diglycerides Enzyme Activation - drug effects Filopodia Gene Knockdown Techniques Hydrophobicity Isoenzymes - metabolism Isoforms Kinases Lymphocytes T Memory Peptides - chemistry Phosphoprotein Phosphatases - metabolism Promoters Protein kinase C Protein Kinase C - metabolism Protein Kinase Inhibitors - pharmacology Protein-tyrosine-phosphatase Proteins protrusions Pseudopodia - drug effects Pseudopodia - metabolism Rats signaling Small Molecule Libraries - pharmacology Tetradecanoylphorbol Acetate - toxicity Transcription
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!