Mypt1-mediated spatial positioning of Bmp2-producing cells is essential for liver organogenesis

Mesodermal tissues produce various inductive signals essential for morphogenesis of endodermal organs. However, little is known about how the spatial relationship between the mesodermal signal-producing cells and their target endodermal organs is established during morphogenesis. Here, we report tha...

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Veröffentlicht in:	Development (Cambridge) 2008-10, Vol.135 (19), p.3209-3218
Hauptverfasser:	Huang, Honghui, Ruan, Hua, Aw, Meng Yuan, Hussain, Alamgir, Guo, Lin, Gao, Chuan, Qian, Feng, Leung, Thomas, Song, Haiwei, Kimelman, David, Wen, Zilong, Peng, Jinrong
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution Animals Animals, Genetically Modified Apoptosis Base Sequence Body Patterning - genetics Body Patterning - physiology Bone Morphogenetic Protein 2 - biosynthesis Bone Morphogenetic Protein 2 - genetics Cell Movement Cell Proliferation DNA - genetics Hepatocytes - cytology Hepatocytes - metabolism Liver - cytology Liver - embryology Liver - metabolism Mesoderm - embryology Mesoderm - metabolism Mutation Myosin-Light-Chain Phosphatase - chemistry Myosin-Light-Chain Phosphatase - genetics Myosin-Light-Chain Phosphatase - metabolism Protein Phosphatase 1 - genetics Protein Phosphatase 1 - metabolism Signal Transduction Zebrafish - embryology Zebrafish - genetics Zebrafish - metabolism Zebrafish Proteins - biosynthesis Zebrafish Proteins - genetics
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