Ginsenoside Rg1 Attenuates Cigarette Smoke-Induced Pulmonary Epithelial-Mesenchymal Transition via Inhibition of the TGF-β1/Smad Pathway

Epithelial-mesenchymal transition (EMT) is a process associated with airway remodeling in chronic obstructive pulmonary disease (COPD), which leads to progressive pulmonary destruction. Panax ginseng is a traditional herbal medicine that has been shown to improve pulmonary function and exercise capa...

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Veröffentlicht in:	BioMed research international 2017-01, Vol.2017 (2017), p.1-12
Hauptverfasser:	Guo, Xue-Jun, Ye, Wenjing, Song, Lin, Gu, Wen, Han, Fengfeng, Xu, Wei, Guan, Si-bin, Liu, Qian
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Asthma Chronic obstructive pulmonary disease Cigarette smoke Cigarettes Destruction Drug dosages E-cadherin Exposure Extracellular matrix Ginseng Ginsenosides Growth factors Herbal medicine Hospitals Inflammation Inhibition Kinases Laboratory animals Lung diseases Medicine Mesenchyme Mortality Obstructive lung disease Oxidative stress Panax ginseng Pathology Rats Respiratory function Respiratory tract Rodents Smad protein Smad2 protein Smad3 protein Smoke Smooth muscle Tissues Transforming growth factor-b1
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