Simian Immunodeficiency Virus SIVmac239, but Not SIVmac316, Binds and Utilizes Human CD4 More Efficiently than Rhesus CD4

Rhesus macaques are used to model human immunodeficiency virus type 1 (HIV-1) infections, but they are not natural hosts of HIV-1 or any simian immunodeficiency virus (SIV). Rather, they became infected with SIV through cross-species transfer from sooty mangabeys in captivity. It has been shown that...

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Veröffentlicht in:	Journal of virology 2017-09, Vol.91 (18)
Hauptverfasser:	Fellinger, Christoph H, Gardner, Matthew R, Bailey, Charles C, Farzan, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CD4 Antigens - metabolism Humans Macaca mulatta Neutralization Tests Protein Binding Simian Immunodeficiency Virus - physiology Virus Attachment Virus-Cell Interactions
Online-Zugang:	Volltext
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